Phenylacetic acid

DB09269ApprovedSmall moleculeNitrogen Binding Agent

Phenylacetic acid is an agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle. Phenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional group.

Chemical structure of Phenylacetic acid
Primary indication
For use as adjunctive therapy for the treatment of acute hyperammonemia and associated encephalopathy in patients with deficiencies in enzymes of the urea cycle.Curator reviewed · 1 structured indication
Formula / weight
C8H8O2 · 136.1479 g/mol (avg)
First approval
United States, 2005
Also known as
.ALPHA.-TOLUIC ACID · .OMEGA.-PHENYLACETIC ACID · 2-PHENYLACETIC ACID · ACETIC ACID, PHENYL- · ANTINEOPLASTON AS 2-1 COMPONENT PHENYLACETIC ACID
Code names
FEMA NO. 2878 · NSC-125718
Brand names
  • Ammonul

Resolves to

Compound
UNIIER5I1W795ACAS103-82-2ChEMBLCHEMBL1044ChEBI30745PubChem999KEGGC07086
Clinical / RWD
RxNorm33332ATCA16AX30
Structure
InChIKeyWLJVXDMOQOGPHL-UHFFFAOYSA-NSMILESOC(=O)CC1=CC=CC=C1
Targets
P11498PC

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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64Drug interactionsStructured to mechanism, not free text
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3Clinical trialsPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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19Marketed productsAcross 1 country and 13 labellers
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1ATC codeIncluding every combination product, plus 8 drug categories
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4+ReferencesStructured and connected to the statements they support
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