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Displaying results 3001 - 3010 of 10000 in total
  1. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    ApprovedInvestigational

    Still docusate is available in over-the-counter products as a common laxative. … Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201].

    International brands: Docusol 100Mixtures: Sennosides 8.6 Mg and Docusate Sodium 50 Mg Tablets, Senna Plus Standardized Senna Concentrate 8.6 mg and Docusate Sodium 50 mg Each
  2. Drug

    Maraviroc

    go.drugbank.com/drugs/DB04835
    ApprovedInvestigational

    interaction between HIV and CCR5. … Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: CELSENTRI® 150 MG, CELSENTRI® 300 MG
  3. Drug

    Abiraterone

    go.drugbank.com/drugs/DB05812
    ApprovedInvestigational

    Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis … and absorption.

    Synonyms: (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol, 17-(3-Pyridyl)androsta-5,16-dien-3beta-olCategories: niraparib and abiraterone, abiraterone and corticosteroids
  4. Drug

    Telmisartan

    go.drugbank.com/drugs/DB00966
    ApprovedInvestigational

    Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular … smooth muscle, ultimately leading to a reduction in arterial blood pressure.

    Synonyms: 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acidMixtures: XIFEN A®80 /10 MG, XIFEN A ®80 /5 MG
  5. Drug

    Erdafitinib

    go.drugbank.com/drugs/DB12147
    ApprovedInvestigational

    with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing chemotherapy, including within 12 … tool kit to treat such a prevalent medical condition.

    Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: BALVERSA 5 MG FİLM KAPLI TABLET, 28 ADET, BALVERSA 3 MG FİLM KAPLI TABLET, 56 ADET
  6. Drug

    Hydroxyprogesterone caproate

    go.drugbank.com/drugs/DB06789
    Approved

    Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. … Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.[L46118] The U.S.

    Synonyms: 17alpha-Caproyloxypregn-4-ene-3,20-dione, 17 Hydroxyprogesterone CapronateMixtures: GRAVIDINONA 2 ML
  7. Drug

    Vilazodone

    go.drugbank.com/drugs/DB06684
    ApprovedInvestigational

    Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. … Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].

    Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor AgonistsProducts: ZİLADONE 10 MG FİLM KAPLI TABLET, 30 ADET, ZİLADONE 20 MG FİLM KAPLI TABLET, 30 ADET
  8. Drug

    Tremelimumab

    go.drugbank.com/drugs/DB11771
    ApprovedInvestigational

    [A253717] By binding to CTLA-4, tremelimumab enhances T cell-mediated killing of tumours and reduces tumour growth. … [L43652] It is also being investigated in other cancers, such as colon cancer, pancreatic cancer, non-small cell lung cancer (NSCLC), and malignant melanoma.

    Categories: CTLA-4-directed Blocking Antibody, Amino Acids, Peptides, and ProteinsProducts: Imjudo 300 mg/15 ml İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adet, Imjudo 25 mg/1.25 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adet
  9. Drug

    Pancrelipase

    go.drugbank.com/drugs/DB00085
    ApprovedInvestigational

    [L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010. … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.

    Mixtures: PANKREOFLAT 170/310 MG GRANÜL (22x2 g poşet), İNTESTİNOL 59,4 MG/21,3 MG/71,1 MG KAPLI TABLET, 120 ADETCategories: Enzymes and Coenzymes, Alimentary Tract and Metabolism
  10. Drug

    Butamirate

    go.drugbank.com/drugs/DB13731
    Investigational

    Categories: Cough and Cold PreparationsProducts: SINECOD 50 MG DEPO TABLET, 10 ADET, CODACTIV 7,5 MG/5 ML SURUP, 100 ML