Search

Displaying results 3001 - 3010 of 10000 in total
  1. Drug

    AV-COVID-19

    go.drugbank.com/drugs/DB15802
    Investigational

    As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine. … The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2 antigens prior to administration.

  2. Drug

    Uridine triacetate

    go.drugbank.com/drugs/DB09144
    Approved

    It can also be used as a rescue therapy if severe side effects present within 96 hours after initiation of therapy. … Additionally, orotic acid from the de novo pyrimidine pathway that cannot be converted to UMP is excreted in the urine, accounting for the common name of the disorder, orotic aciduria.

  3. Drug

    MK-886

    go.drugbank.com/drugs/DB16739
    Experimental

    MK-886 is an experimental inhibitor of leukotriene synthesis.

  4. Drug

    MK-4965

    go.drugbank.com/drugs/DB08460
    Experimental

    MK-4965 is an HIV-1 reverse transcriptase inhibitor.

  5. Drug

    Sinapic acid

    go.drugbank.com/drugs/DB08587
    Experimental

    Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. It is also a constituent of propolis.

    Synonyms: (E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoic acid
  6. Drug

    Anethole trithione

    go.drugbank.com/drugs/DB13853
    Approved

    Unfortunately, many of the specific mechanisms of action to these activities have yet to be formally elucidated, which means that while studies are ongoing, ATT itself is not necessarily formally indicated … for many of these aforementioned functions at this time and is only used in limited regions around the world.

  7. Drug

    Nitroarginine

    go.drugbank.com/drugs/DB04223
    Investigational

    (Neurochem Res 1995:200(4):451-6)

    Synonyms: L-NNA, Ngamma-Nitro-L-arginine
  8. Drug

    Mitemcinal

    go.drugbank.com/drugs/DB06587
    Investigational

    Mitemcinal (GM-611) is a novel erythromycin-derived prokinetic agent that acts as an agonist at the motilin receptor.

  9. Drug

    MK-8777

    go.drugbank.com/drugs/DB18904
    Investigational

    (174001/P05704/MK-8777-001)). … MK-8777 is under investigation in clinical trial NCT00610649 (Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder

    Synonyms: 5H,7H-PYRIDO(3,2-F)PYRROLO(2,1-C)(1,4)OXAZEPIN-5-ONE, 8,9,9A,10-TETRAHYDRO-, (9AS)-
  10. Drug

    Umbralisib

    go.drugbank.com/drugs/DB14989
    ApprovedInvestigationalWithdrawn

    It was marketed as Ukoniq by TG Therapeutics and has been approved for the treatment of relapsing and refractory marginal cell lymphoma and follicular lymphoma in adults. … [L31863] Umbralisib inhibits casein kinase, a primary regulator of protein translation, kinase-1ε, distinguishing it from other lymphoma treatments.