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Troglitazone
go.drugbank.com/drugs/DB00197ApprovedWithdrawnTroglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by [pioglitazone] and [rosiglitazone].
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesBioallethrin
go.drugbank.com/drugs/DB13746ApprovedWithdrawnBioallethrin is a synthetic pyrethroid used as a pesticide against household pest insects such as mosquitoes, houseflies and cockroaches. It is claimed to have low mammalian toxicity. … A mixture containing only S-forms of allethrin is referred to as esbioallethrin or S-bioallethrin.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesOral Malodor (Halitosis)
go.drugbank.com/conditions/DBCOND0035973Drugs: DequaliniumSynonyms: Bad Breath, Bad breath - halitosisNamilumab
go.drugbank.com/drugs/DB13037InvestigationalNamilumab has been used in trials studying the treatment of Plaque Psoriasis and Rheumatoid Arthritis.
Chromium picolinate
go.drugbank.com/drugs/DB11255ApprovedChromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. … Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss.
Mixtures: Medi-10, GNC Lecithin 1200 Plus softgel CapsuleDicirenone
go.drugbank.com/drugs/DB20938ExperimentalThe usage of the INN stem '-renone' in the name indicates that Dicirenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. … Dicirenone has a monoisotopic molecular weight of 428.26 Da.
Resorcinol
go.drugbank.com/drugs/DB11085ApprovedInvestigationalIt is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses … Although it is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of formal therapeutic
Mixtures: BUCO-BLEU KOLLUTUVAR, 15 ML, DG Health Feminine Anti-itchSynonyms: m-Hydroquinone, m-hydroxyphenolVeliflapon
go.drugbank.com/drugs/DB16346InvestigationalVeliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina).
Mavorixafor
go.drugbank.com/drugs/DB05501ApprovedInvestigational[L50642] It was first approved by the FDA on April 30, 2024, for the treatment of warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome, a genetic immunodeficiency disorder characterized … [L50642] As CXCR4 mutations have also been implicated in human immunodeficiency virus (HIV), Waldenstrom’s macroglobulinemia (WM), B-cell non-Hodgkin lymphoma, and solid tumours, including melanoma,
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesGlycyrrhizic acid
go.drugbank.com/drugs/DB13751ApprovedInvestigational[A33062] From January 2014, glycyrrhizic acid as part of the licorice extract was approved by the FDA as an existing food sweetener. … [T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of chronic hepatitis.