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Chromium Cr-51
go.drugbank.com/drugs/DB11140ApprovedInvestigationalChromium Cr-51 is an isotope of chromium that has been used as a radioactive label for decades. … It is used as a diagnostic radiopharmaceutical agent in nephrology to determine glomerular filtration rate,[A249765,A249770] and in hematology to determine red blood cell volume or mass, study the red
Mixtures: Tricare Prenatal 2-part Daily Prenatal Vitamin SystemProducts: CHROMIUM [51 CR] EDTA INJECTION 3.7 MBq/mlDesfesoterodine
go.drugbank.com/drugs/DB15578InvestigationalDesfesoterodine is a metabolite of [tolterodine].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: 5-HydroxymethyltolterodinePenciclovir
go.drugbank.com/drugs/DB00299ApprovedDisplaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. … Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine, 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanineMexazolam
go.drugbank.com/drugs/DB15489Investigational[A184910] The use of benzodiazepines in the treatment of anxiety is generally a second line measure.[A184910] … Mexazolam (CS-386) is a benzodiazepine indicated for the treatment of anxiety with or without psychoneurotic conditions.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: SEDOXIL 1 MGTegoprazan
go.drugbank.com/drugs/DB16690Investigational[A234215, A234220] This drug is a potent and high-selective potassium-competitive acid blocker (P-CAB) with a fast onset of action and the ability to control gastric pH for a prolonged period of time. … Tegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related gastrointestinal diseases.
Categories: Heterocyclic Compounds, 1-RingSynonyms: K-CABPolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429]. … Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label].
Synonyms: Polymyxin B, Polimixina BInternational brands: Polomyxin BOmpenaclid
go.drugbank.com/drugs/DB18819InvestigationalRGX-202 is a recombinant AAV8 that contains a vector genome encoding a miniaturized dystrophin protein (microdystrophin).
Synonyms: 3-guanidinopropionic acid, RGX-202Amprolium
go.drugbank.com/drugs/DB11374ExperimentalVet approvedAmprolium is a coccidiostat used in poultry.
Synonyms: 1-((4-amino-2-Propyl-5-pyrimidinyl)methyl)-2-picolinium chlorideCategories: Heterocyclic Compounds, 1-RingDimethyl sulfone
go.drugbank.com/drugs/DB14090InvestigationalMixtures: Cosamine Plus Forte M Powder, GLUCONITRIN F®Products: Live-well™ OsteMSM 500 Tablet, Live-well™ OsteMSM 1000 TabletLorcaserin
go.drugbank.com/drugs/DB04871ApprovedInvestigationalWithdrawnIn February 2020, the FDA issued a Drug Safety Communication requesting the manufacturer of Belviq (lorcaserin hydrochloride tablets, 10 mg) and Belviq XR (lorcaserin hydrochloride extended-release tablets … , 20 mg) to voluntarily withdraw these products from the U.S. market, and the company has submitted a request to voluntarily withdraw the drug.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring