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Landiolol
go.drugbank.com/drugs/DB12212ApprovedInvestigationalLandiolol is a rapid-acting beta (β)-1 adrenergic receptor blocker that blocks the positive chronotropic effect of the beta-1 selective agonist norepinephrine. … [L51938] It works to reduce the heart rate, myocardial contractility, and conduction velocity.
Lanthanum carbonate
go.drugbank.com/drugs/DB06792ApprovedIt is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to dietary phosphate and preventing its absorption in the intestine.[L50733] … Lanthanum carbonate is a phosphate binder marketed under the trade name _Fosrenol_ by Shire Pharmaceuticals.
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2
go.drugbank.com/bio_entities/BE0009594TargetHumansInositol 1,4,5-trisphosphate-gated calcium channel that upon inositol 1,4,5-trisphosphate binding transports calcium from the endoplasmic reticulum lumen to cytoplasm. Exists in two states; a long-lived closed state where the channel is ...
Synonyms: IP3 receptor isoform 2, Type 2 InsP3 receptorNilotinib
go.drugbank.com/drugs/DB04868ApprovedInvestigationalA Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant to treatment with imatinib (Gleevec
Venetoclax
go.drugbank.com/drugs/DB11581ApprovedInvestigationalProteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process [A18565], [A18566]. … Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic lymphoma [FDA label]. CLL is the most prevalent leukemia diagnosed in Western countries [A40022].
Permethrin
go.drugbank.com/drugs/DB04930ApprovedInvestigationalA pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Japanese Encephalitis Virus Vaccine Inactivated
go.drugbank.com/drugs/DB19294ApprovedWithdrawnSynonyms: JE-VAXMixtures: Je-vax 1 DoseNiacinamide ascorbate
go.drugbank.com/drugs/DB14486ApprovedNutraceuticalWithdrawnMixtures: Se-Natal, Se-Natal OneMiocamycin
go.drugbank.com/drugs/DB13287ApprovedIt has shown to be effective against several gram-positive and gram-negative microbes and may be useful in the treatment of upper and lower respiratory tract infections, and urogenital tract infections … This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia [L5737].
Lumateperone
go.drugbank.com/drugs/DB06077ApprovedInvestigational[A189093] It has a unique receptor binding profile and differs from other antipsychotics in that it modulates glutamate, serotonin and dopamine, which are all neurotransmitters that contribute to the pathophysiology … Schizophrenia is a complex mental illness and impacts approximately 1% of the population.
Categories: Dopamine D2 Receptor Agonists, Serotonin Receptor Antagonists