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Displaying results 3051 - 3060 of 10000 in total

Target
Serotonin Receptors
go.drugbank.com/bio_entities/BE0004862
TargetHumans
G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:22957663, PubMed:3138543, PubMed:33762731, PubMed:37935376, PubMed:37935377, PubMed:8138923, PubMed:8393041). Also functions as a receptor for various drugs and psych...
Synonyms: 5-HT3-E
Drug
Etranacogene dezaparvovec
go.drugbank.com/drugs/DB16791
ApprovedInvestigational
[L44161] It is additionally notable for its cost per treatment - approximately 3.5 million USD - earning it the title of most expensive drug in the world. … The therapy involves a one-time infusion of a viral vector carrying a codon-optimized DNA sequence of the gain-of-function Padua variant of human Factor IX controlled by a liver-specific promotor 1.
Drug
Chlormadinone acetate
go.drugbank.com/drugs/DB15903
ApprovedWithdrawn
Chlormadinone acetate is a progesterone derivative first synthesized in 1961. … In the US, chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and C-Quens.
Mixtures: LUTORAL-E
Drug
Taurocholic acid
go.drugbank.com/drugs/DB04348
Approved
It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
Mixtures: Lax-BO TabCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitors
Drug
Bordetella pertussis fimbriae 2/3 antigen
go.drugbank.com/drugs/DB10790
ApprovedInvestigational
Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct
Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, 3 ANTIGENSynonyms: Bordetella pertussis fimbriae 2/3 antigen, Bordetella pertussis fimbriae 2/3 vaccine, inactivated
Drug
Pentoxyverine
go.drugbank.com/drugs/DB11186
ApprovedWithdrawn
Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and local anesthetic properties. … [L43942] Other forms of pentoxyverine citrate continue to be marketed.
Mixtures: Corzall PE, Pancold AProducts: PENTOXYVERIN AL 19MG/ML, PENTOXYVERIN AL 1.35 MG/ML
Drug
Ziconotide
go.drugbank.com/drugs/DB06283
ApprovedInvestigational
Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail _Conus magus_ comprising 25 amino acids with three disulphide bonds. … [A202829, A202832] Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling.
Categories: Compounds used in a research, industrial, or household setting, Calcium Channels, N-Type
Drug
Pivmecillinam
go.drugbank.com/drugs/DB01605
ApprovedInvestigational
Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa.
Categories: Heterocyclic Compounds, 2-Ring
Drug
LSZ-102
go.drugbank.com/drugs/DB15362
Investigational
LSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers).
Categories: Heterocyclic Compounds, 1-Ring
Drug
Pancrelipase amylase
go.drugbank.com/drugs/DB11065
ApprovedInvestigational
[T177] The pancrelipase amylase is a single polypeptide chain containing two SH groups and four disulfide bridges. … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.
Mixtures: Viokase Pwr, Creon 8 CapSynonyms: Amylase A, 1,4-alpha-D-Glucan glucanohydrolase