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Pancrelipase amylase is a lipase used to treat pancreatic exocrine insufficiency. Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases.
- Mechanism
- Curator reviewed · 1 reference
The pancrelipase amylase acts by replacing the lack of physiological amylase. The amylase activity is done by the hydrolyzation of the alpha 1-4 linkages in the polysaccharides of three or more linked glucose units. The linkages alpha 1-6 are not hydrolyzed and thus, the starch is only reduced to lower molecule compounds.
- Primary indication
- Please refer to DB00085.Curator reviewed · 4 structured indications
- Formula / weight
- 57086.0 Da
- First approval
- Canada, 2011 · United States, 2009
- Also known as
- alpha-Amylase · alpha-amylase (porcine) · Alpha-amylase swine pancreas · alpha-Amylases · Amylase A
- Brand names
- Cotazym
- Creon
- Pancrease MT
- Pancreaze
- Pertzye
- Viokace
- Zenpep
Resolves to
What you can answer from here — as of April 02, 2025
Which other approved drugs treat the same conditions as Pancrelipase amylase, and which companies have late-stage candidates in those indications?