Chlormadinone acetate

DB15903ApprovedWithdrawnSmall molecule

Chlormadinone acetate is a progestin indicated in combination with an estrogen for birth control. Chlormadinone acetate is a progesterone derivative first synthesized in 1961.

Mechanism: Pharmacologically active on Progesterone receptor
Curator reviewed
Formula / weight: C₂₃H₂₉ClO₄ · 404.93 g/mol (avg)

Resolves to

Compound

UNII0SY050L61NCAS302-22-7ChEMBLCHEMBL110691ChEBI31394KEGGC12729

Clinical / RWD

RxNorm2369

Structure

InChIKeyQMBJSIBWORFWQT-DFXBJWIESA-NSMILES[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=C(Cl)C2=CC(=O)CC[C@]12C

Targets

P06401PGR

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

407Drug interactionsStructured to mechanism, not free text

4Clinical trialsPhase, status and sponsor resolved per trial

40ContraindicationsEach with its own population and attribute set

21Marketed productsAcross 2 countries and 5 labellers

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Chlormadinone acetate, and which of those have an active Phase 3 trial?

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