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Suprofen
go.drugbank.com/drugs/DB00870ApprovedWithdrawnAn ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Naldemedine
go.drugbank.com/drugs/DB11691ApprovedInvestigationalNaldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation. … It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier.
Ondelopran
go.drugbank.com/drugs/DB12585InvestigationalOndelopran has been used in trials studying the treatment of Alcohol Dependence.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Alcohol DependencePotassium bitartrate
go.drugbank.com/drugs/DB11107ApprovedInvestigationalPotassium bitartrate has a long history of medical use as a laxative administered as a rectal suppository and is an approved third-class OTC drug in Japan. … Potassium bitartrate was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.[L14120]
Light-harvesting protein B-800/820 beta chain
go.drugbank.com/bio_entities/BE0003922TargetRhodopseudomonas acidophilaAntenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
Synonyms: LH3 complex subunit betaMotexafin gadolinium
go.drugbank.com/drugs/DB05428InvestigationalMotexafin gadolinium is studied in the treatment of cancer by Pharmacyclics.
Categories: Compounds used in a research, industrial, or household settingSynthetic Conjugated Estrogens, A
go.drugbank.com/drugs/DB09317ApprovedPharmacologic estrogen products are available in a variety of formats. … However, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control
Berahyaluronidase alfa
go.drugbank.com/drugs/DB22790ApprovedInvestigationalIt is used in a fixed-dose combination with [pembrolizumab] for subcutaneous injection. … This combination was approved by the US FDA in September 2025 and is indicated for various solid tumors in adults and pediatric patients 12 years and older, offering a subcutaneous option for indications
Bergamot oil
go.drugbank.com/drugs/DB14335InvestigationalBergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Categories: Compounds used in a research, industrial, or household setting, Complex MixturesTrimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalIn dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate. … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ).
Synonyms: N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamide