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Displaying results 3071 - 3080 of 10000 in total
  1. Drug

    Ferric hydroxide

    go.drugbank.com/drugs/DB13423
    Investigational

    Products: FERIFER 100 MG/5 ML ORAL COZELTI ICEREN KAŞIK, 20 ADET, FERIFER-40 ORAL COZELTI 40 MG/5 ML KAŞIK, 10 ADET
  2. Drug

    Somatostatin

    go.drugbank.com/drugs/DB09099
    ApprovedInvestigationalWithdrawn

    Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 (SST-28), an extended SST-14 sequence to the N-terminus [A20384]. … The actions of somatostatin are mediated via signalling pathways of G protein-coupled somatostatin receptors.

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: Synthetic somatostatin-14
  3. Drug

    Gemifloxacin

    go.drugbank.com/drugs/DB01155
    ApprovedInvestigational

    Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. … It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.

    Categories: Heterocyclic Compounds, 2-Ring, 4-QuinolonesProducts: ONFACT 320 MG FİLM TABLET, 5 ADET, FACTIVE 320 MG FİLM TABLET, 5 ADET
  4. Drug

    Tenofovir disoproxil

    go.drugbank.com/drugs/DB00300
    ApprovedInvestigational

    Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase … This drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label].

    Mixtures: STRIBILD FILM COATED TABLET 150 MG/150 MG/200 MG/245 MG, TRUVADA 200 MG/245 MG FILM TABLET, 30 ADETCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  5. Drug

    Follitropin

    go.drugbank.com/drugs/DB00066
    ApprovedInvestigational

    The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24. … with significantly higher estradiol (E2) levels.

    Mixtures: PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 10 ADET, Puregon 50 I.U.Synonyms: FSH-a, FSH-b
  6. Drug

    Aflibercept

    go.drugbank.com/drugs/DB08885
    ApprovedInvestigational

    gamma 1 (IgG1). … [A261276] It contains approximately 15% glycosylation to give a total molecular weight of 115 kDa.

    Products: EYLEA 40 MG/ML INTRAVITREAL ENJEKSIYON ICIN COZELTI ICEREN FLAKON, 1 ADET, ZALTRAP CONCENTRATE FOR SOLUTION FOR INFUSION 25 MG/ML
  7. Drug

    Carbetocin

    go.drugbank.com/drugs/DB01282
    ApprovedInvestigational

    Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.

    Synonyms: 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin, deamino-2-O-methyltyrosine-1-carbaoxytocinProducts: KARPAVER 100 MCG/1 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, PABAL 100 MCG/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 5 ADET
  8. Drug

    Lithium carbonate

    go.drugbank.com/drugs/DB14509
    ApprovedInvestigational

    Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. … Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: LITHURIL 300 MG KAPSUL, 100 ADET, LİTOMAKS 300 MG SERT KAPSÜL, 100 ADET
  9. Drug

    Edetate calcium disodium anhydrous

    go.drugbank.com/drugs/DB14598
    ApprovedInvestigational

    [L12774] It is on the World Health Organization Model List of Essential Medicines.[A204173] Edetate calcium disodium was granted FDA approval on 16 July 1953.[L12774] … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: LIBENTA AMPUL 2ML, 10 ADET, EDETATO CALCICO DISODICO 20%
  10. Drug

    Bromocriptine

    go.drugbank.com/drugs/DB01200
    ApprovedInvestigationalWithdrawn

    Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. … [L43942,L43947] It continues to be used for the indications mentioned above.

    Categories: Adrenergic alpha-2 Receptor Agonists, Adrenergic alpha-1 Receptor AgonistsSynonyms: 2-bromo-α-ergokryptin, 2-bromo-α-ergocryptine