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L-Acetylleucine
go.drugbank.com/drugs/DB16956ApprovedInvestigationalLevacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo. … [A264439] In September 2024, the FDA approved levacetylleucine for the treatment of select patients with NPC.[L51444]
Synonyms: N-acetyl-l-leucine, L-leucine, n-acetyl-Tranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalTranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. … A propylamine formed from the cyclization of the side chain of amphetamine.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Antidepressive Agents Indicated for DepressionGliquidone
go.drugbank.com/drugs/DB01251ApprovedGliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. … This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
International brands: Ka Rui LinCategories: Drugs Used in DiabetesMeningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine
go.drugbank.com/drugs/DB10061ApprovedInvestigational[A253277] Several serogroups of _N. meningitidis_ - A, B, C, Y, and W-135 - known to cause meningococcal infections have been identified. … diphtheriae_ CRM197 protein carrier, resulting in four drug substances contained in each dose of vaccine.
Synonyms: Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccineCobalamin
go.drugbank.com/drugs/DB14098ApprovedInvestigationalMixtures: Nephron FA, Nephron FACategories: Heterocyclic Compounds with 4 or More RingsKetazolam
go.drugbank.com/drugs/DB01587ApprovedWithdrawnKetazolam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. Ketazolam is not approved in Canada or America.
Avutometinib
go.drugbank.com/drugs/DB15254ApprovedInvestigational[A273948] Avutometinib was approved by the US FDA in May 2025 in a co-package alongside [defactinib] (called Avmapki Fakzynja) for the treatment of recurrent KRAS-mutated low-grade serous ovarian cancer … [L53203,L53198] The MAPK pathway is implicated in variety of cancers, playing a key role in tumor cell proliferation, differentiation and survival.
Synonyms: N-(3-fluoro-4-((4-methyl-2-oxo-7-((pyrimidin-2-yl)oxy)-2H-1-benzopyran-3-yl)methyl)pyridin-2-yl)-N'-methylsulfuric diamide, Sulfamide, N-(3-fluoro-4-((4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl)methyl)-2-pyridinyl)-N'-methyl-Landiolol
go.drugbank.com/drugs/DB12212ApprovedInvestigational[A264733,A264738] First approved in Japan in 2002 [A264758] for the treatment of intraoperative tachyarrhythmias,[A264733] landiolol was approved in Canada in April 2024 [L51938] and in the US in November … for β-1 adrenergic receptors over β-2 receptors.
Recombinant Cholera Toxin B Subunit
go.drugbank.com/drugs/DB11643ApprovedInvestigationalRecombinant Cholera Toxin B Subunit is an ingredient in the EMA-authorised product Dukoral.
Categories: Compounds used in a research, industrial, or household settingMMDA
go.drugbank.com/drugs/DB01442ExperimentalIllicitMMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. … MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates