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Olmesartan
go.drugbank.com/drugs/DB00275ApprovedInvestigationalARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling. … [A175330] It was developed by Daiichi Sankyo Pharmaceuticals and approved in 2002.[A175345, L12882]
Mixtures: OLMESARTAN CO 1A PH20/25MG, OLMESARTAN CO 1A PH20/25MGCategories: Agents Acting on the Renin-Angiotensin System, olmesartan medoxomil and diureticsLinagliptin
go.drugbank.com/drugs/DB08882ApprovedInvestigationalLinagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050 … Linagliptin was approved by the FDA on May 2, 2011[L9557].
Mixtures: Glyxambi Film-Coated Tablets 10mg/5mg, GLYXAMBI 10MG/5 MG FİLM KAPLI TABLET, 30 TABLETCategories: Alimentary Tract and Metabolism, metformin and linagliptinBenzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigationalBenzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
Mixtures: Bus and Classroom Yellow, Care Bus and Classroom YellowCategories: Antipruritics and Local Anesthetics, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseCiprofloxacin
go.drugbank.com/drugs/DB00537ApprovedInvestigational[A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections. … [L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.[L6463]
Mixtures: Ciprofloxacin and Dexamethasone, Ciprofloxacin and DexamethasoneCategories: ciprofloxacin and tinidazole, ciprofloxacin and ornidazoleSpironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigational[A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.[A178243] … It binds to mineralocorticoid receptors and functions as aldosterone antagonists.[A178192] It promotes sodium and water excretion and potassium retention.
Mixtures: SPIRO COMP RATIO 50MG/20MG, SPIRO COMP RATIO 50MG/20MGCategories: Hormones, Hormone Substitutes, and Hormone AntagonistsPrazosin
go.drugbank.com/drugs/DB00457ApprovedInvestigationalPrazosin is a drug used to treat hypertension. Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988. … Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and associated nightmares.[A176618, A176621, A176624]
Categories: prazosin and diuretics, Alpha-Adrenoreceptor Antagonists and DiureticsProducts: Nu-prazo Tab 1mg, Nu-prazo Tab 2mgMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527] … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.
Mixtures: IMPLICOR 25MG/5MG FILM-COATED TABLETS, IMPLICOR 50MG/5MG FILM-COATED TABLETSCategories: metoprolol and thiazides, metoprolol and felodipineFelodipine
go.drugbank.com/drugs/DB01023ApprovedBy inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. … It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Mixtures: Altace Plus Felodipine 2.5mg + 2.5mg, DELMUNO 2.5/2.5MGCategories: ramipril and felodipine, metoprolol and felodipineAzathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigationalAzathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic … [A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesProducts: AZATHIOPRIN DURA N 25MG, AZATHIOPRIN DURA N 50MGBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: CIBADREX 20MG/25MG, CIBADREX 20MG/25MGCategories: ACE Inhibitors and Diuretics, benazepril and diuretics