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Human vaccinia virus immune globulin
go.drugbank.com/drugs/DB14112ApprovedInvestigationalThe IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent/detergent-treated to sterilize the compound [A33814]. … Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human product that is only available in very limited quantities - all factors that may intervene with
Categories: Immunoglobulin G, Human Immunoglobulin GVusolimogene oderparepvec
go.drugbank.com/drugs/DB23008ApprovedInvestigational[L64061] The virus is engineered to express a fusogenic glycoprotein derived from gibbon ape leukemia virus (GALV-GP-R–) and human granulocyte-macrophage colony-stimulating factor (GM-CSF), and has its … promoting dendritic cell and monocyte activation to drive an anti-tumor immune response.
Moxetumomab pasudotox
go.drugbank.com/drugs/DB12688ApprovedInvestigationalThis antibody was used to generate a recombinant immunotoxin in which a stabilized Fv segment by a disulfide bond is fused to the _Pseudomonas_ exotoxin A (PE38) which does not have the cell-binding portion … [A38864] MxP appears as an improved form of BL22 by the mutation of the Fv region and the antibody phage-displayed. As well the residues SSY in the heavy chain are mutated to THW.
Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)
go.drugbank.com/drugs/DB10991ApprovedInvestigationalBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus
Mixtures: HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 10 ADET, HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 10 ADETCarprofen
go.drugbank.com/drugs/DB00821ApprovedVet approvedWithdrawnCarprofen was previously used in human medicine for over 10 years (1985-1995). … It was generally well tolerated, with the majority of adverse effects being mild, such as gastro-intestinal pain and nausea, similar to those recorded with aspirin and other non-steroidal anti-inflammatory
Bendroflumethiazide
go.drugbank.com/drugs/DB00436ApprovedInvestigationalA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders.
Mixtures: CORGARETIC (NADOLOL/ BENDROFLUMETIAZIDA) 80/5 MGProducts: Naturetin 5mgVutrisiran
go.drugbank.com/drugs/DB16699ApprovedInvestigational[A249010] More than 130 TTR mutations have been identified so far,[A249015] but the most common one is the replacement of valine with methionine at position 30 (Val30Met). … [A249010] TTR mutations lead to the formation of misfolded TTR proteins, which form amyloid fibrils that deposit in different types of tissues.
Tafenoquine
go.drugbank.com/drugs/DB06608ApprovedInvestigational[A35677] It was FDA approved on July 20, 2018.[L3770] … Tafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy group.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesTick-Borne Encephalitis, European
go.drugbank.com/conditions/DBCOND0144103Synonyms: Encephalitis due to tick-borne encephalitis virus (navigational concept)Fosnetupitant
go.drugbank.com/drugs/DB14019ApprovedInvestigationalGenerally, 25% to 30% of patients with a diagnosis of cancer receive chemotherapy as a treatment modality and 70% to 80% of these patients undergoing chemotherapy treatment may experience nausea and vomiting
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates