Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Boostrix, Infanrix, Kinrix, Pediarix
Generic Name
Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)
DrugBank Accession Number
DB10991
Background

Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus that infects the mucosal layers of the human respiratory tract.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Toxoid
Synonyms
  • Bordetella pertussis toxoid vaccine, inactivated

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
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Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ADACEL 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADETBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (2.5 mcg/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (5 mcg/0.5mL) + Bordetella pertussis fimbriae 2/3 antigen (5 mcg/0.5mL) + Bordetella pertussis pertactin antigen (3 mcg/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 Lf/0.5mL) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 Lf/0.5mL)Injection, solutionIntramuscularSANOFİ PASTEUR AŞI TİC. A.Ş.2020-08-14Not applicableTurkey flag
ADACEL POLIO 0,5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (2.5 mcg/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (5 mcg/0.5mL) + Bordetella pertussis fimbriae 2/3 antigen (5 mcg/0.5mL) + Bordetella pertussis pertactin antigen (3 mcg/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 Lf/0.5mL) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 Lf/0.5mL) + Poliovirus type 1 antigen (formaldehyde inactivated) (40 DU/5mL) + Poliovirus type 2 antigen (formaldehyde inactivated) (8 DU/5mL) + Poliovirus type 3 antigen (formaldehyde inactivated) (32 DU/5mL)Injection, suspensionIntramuscularSANOFİ PASTEUR AŞI TİC. A.Ş.2020-08-14Not applicableTurkey flag
BoostrixBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis pertactin antigen (formaldehyde inactivated) (2.5 ug/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 [iU]/0.5mL) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2.5 [iU]/0.5mL)SuspensionIntramuscularA-S Medication Solutions2009-07-24Not applicableUS flag
BoostrixBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis pertactin antigen (formaldehyde inactivated) (2.5 ug/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 [iU]/0.5mL) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2.5 [iU]/0.5mL)SuspensionIntramuscularA-S Medication Solutions2009-07-24Not applicableUS flag
BoostrixBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis pertactin antigen (formaldehyde inactivated) (2.5 ug/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 [iU]/0.5mL) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2.5 [iU]/0.5mL)SuspensionIntramuscularGlaxoSmithKline Biologicals SA2009-07-24Not applicableUS flag
BOOSTRIX 0,5 ML IM ENJEKSIYON ICIN SUSPANSIYON ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADETBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (8 mcg/0.5ml) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 mcg/0.5ml) + Bordetella pertussis pertactin antigen (2.5 mcg/0.5ml) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (20 IU/0.5ml) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 IU/0.5ml)SuspensionIntramuscularGLAXOSMİTHKLİNE İLAÇLARI SAN. VE TİC. A.Ş.2020-08-14Not applicableTurkey flag
BOOSTRIX POLIOBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis pertactin antigen (formaldehyde inactivated) (2.5 ug/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 [iU]/0.5mL) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2.5 [iU]/0.5mL)Injectionบริษัท แกล็กโซสมิทไคล์น (ประเทศไทย) จำกัด2010-04-12Not applicableThailand flag
BOOSTRIX POLIO 0,5 ML IM ENJEKSIYON ICIN SUSPANSIYON ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADETBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (8 mcg/0.5ml) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 mcg/0.5ml) + Bordetella pertussis pertactin antigen (2.5 mcg/0.5ml) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (20 IU/0.5ml) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 IU/0.5ml) + Poliovirus type 1 antigen (formaldehyde inactivated) (40 DU/0.5ml) + Poliovirus type 2 antigen (formaldehyde inactivated) (8 DU/0.5ml) + Poliovirus type 3 antigen (formaldehyde inactivated) (32 DU/0.5ml)SuspensionIntramuscularGLAXOSMİTHKLİNE İLAÇLARI SAN. VE TİC. A.Ş.2020-08-14Not applicableTurkey flag
HEXAXIMBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (25 mcg/0.5ml) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (25 mcg/0.5ml) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (40 IU/0.5ml) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (20 IU/0.5ml) + Haemophilus influenzae b polysaccharide-tetanus conjugate (12 mcg/0.5ml) + Hepatitis B Vaccine (Recombinant) (10 mcg/0.5ml) + Poliovirus type 1 antigen (formaldehyde inactivated) (40 [D'ag'U]/0.5ml) + Poliovirus type 2 antigen (formaldehyde inactivated) (8 [D'ag'U]/0.5ml) + Poliovirus type 3 antigen (formaldehyde inactivated) (32 [D'ag'U]/0.5ml)Injection, suspensionIntramuscularบริษัท ซาโนฟี่ ปาสเตอร์ จำกัด2017-05-31Not applicableThailand flag
HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADETBordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (25 µg) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (25 µg) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (40 IU) + Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (20 IU) + Haemophilus influenzae type B capsular polysaccharide meningococcal outer membrane protein conjugate antigen (12 µg) + Hepatitis B Vaccine (Recombinant) (10 µg) + Poliovirus type 1 antigen (formaldehyde inactivated) (40 D) + Poliovirus type 2 antigen (formaldehyde inactivated) (8 D) + Poliovirus type 3 antigen (formaldehyde inactivated) (32 D)Injection, solutionIntramuscularSANOFİ PASTEUR AŞI TİC. A.Ş.2020-08-14Not applicableTurkey flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
QSN5XO8ZSU
CAS number
Not Available

References

General References
Not Available
PubChem Substance
347911073
RxNav
1300186

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingPreventionHuman Papillomavirus Infections / Human Papillomavirus-Related Cervical Carcinoma1
4CompletedPreventionAcellular Pertussis / Diphtheria / Diphtheria-Tetanus-acellular Pertussis Vaccines / Tetanus1
4CompletedPreventionAcellular Pertussis / Diphtheria / Haemophilus Influenzae Type B / Poliomyelitis / Tetanus / Viral Hepatitis B2
4CompletedPreventionAcellular Pertussis / Diphtheria / Poliomyelitis / Tetanus / Viral Hepatitis B1
4CompletedPreventionAcellular Pertussis / Diphtheria / Tetanus5
4CompletedPreventionBCG Infection / Immune Responses / Vaccine Reaction1
4CompletedPreventionDiphtheria-Tetanus-acellular Pertussis Vaccines1
4CompletedPreventionDiphtheria / Haemophilus Infections / Pertussis / Poliomyelitis / Tetanus1
4CompletedPreventionDiphtheria / Haemophilus Influenzae Type B / Pertussis / Poliomyelitis / Tetanus1
4CompletedPreventionDiphtheria / Pertussis / Poliomyelitis / Tetanus3

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionIntramuscular
SuspensionIntramuscular
Injection
Injection, powder, for suspensionIntramuscular
Injection, suspensionIntramuscular
InjectionIntramuscular
Injection, suspensionIntramuscular; Subcutaneous
Injection, suspension
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on December 01, 2015 20:04 / Updated on June 12, 2020 16:53