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Elafibranor
go.drugbank.com/drugs/DB05187ApprovedInvestigationalElafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist [A263833] that works to inhibit bile acid synthesis. … [L50773] The drug was also approved by the EMA on September 23, 2024.[L51878]
Categories: Bile and Liver Therapy, Alimentary Tract and MetabolismMagaldrate
go.drugbank.com/drugs/DB08938ApprovedInvestigationalWithdrawnMagaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Mixtures: M A L D I M, MAGALDRATE CON SIMETRICONACategories: Alimentary Tract and Metabolism, magaldrate and antiflatulentsRelebactam
go.drugbank.com/drugs/DB12377ApprovedInvestigational[A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal … [A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge.
Categories: imipenem, cilastatin and relebactamTicagrelor
go.drugbank.com/drugs/DB08816ApprovedInvestigational[A2903] Unlike [clopidogrel], ticagrelor is not a prodrug.[A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU,[L14207]. … Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y<sub>12</sub> receptor antagonism.
Categories: Blood and Blood Forming Organs, Nucleic Acids, Nucleotides, and NucleosidesProducts: Trixevas 90mg FC Tablet, BRILINTA 90MG FILM-COATED TABLETTerpin hydrate
go.drugbank.com/drugs/DB13163ApprovedWithdrawnTerpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting with acute or chronic bronchitis, and related pulmonary conditions. … It was popular in the United States since the late nineteenth century, but was removed from marketed medications in the 1990s after FDA stated that "based on evidence currently available, there are inadequate
Rasagiline
go.drugbank.com/drugs/DB01367ApprovedInvestigationalRasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Synonyms: (1R)-N-propargylindan-1-amine, (R)-N-2-Propynyl-1-indanamineCategories: Compounds used in a research, industrial, or household settingHexylcaine
go.drugbank.com/drugs/DB00473ApprovedWithdrawnHexylcaine has been discontinued in the US market. … Patients experience an overdose may present with headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function.
Metipranolol
go.drugbank.com/drugs/DB01214ApprovedWithdrawnA beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Categories: Beta Blocking Agents and Thiazides, Antiglaucoma Preparations and MioticsPancreatic Metastatic Cancer
go.drugbank.com/conditions/DBCOND0070216Synonyms: Secondary malignant deposit in pancreasDeutetrabenazine
go.drugbank.com/drugs/DB12161ApprovedInvestigationalThe most prominent physical symptom of HD that may increase the risk of injury is chorea, which is an involuntary, sudden movement that can affect any muscle and flow randomly across body regions [A32046 … It was approved by FDA in April 2017 and is marketed under the trade name Austedo as oral tablets.
Categories: Tetrabenazine and isomer