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Displaying results 3091 - 3100 of 5900 in total
  1. Drug

    Etravirine

    go.drugbank.com/drugs/DB06414
    ApprovedInvestigational

    On January 18, 2007, the FDA granted accelerated approved for the use of etravirine 100mg tablets in the treatment of adult HIV-1 infection documented to be resistant to therapy with other NNRTIs and antiretroviral … Patients are advised to immediately contact their healthcare provider if a rash develops.

  2. Drug

    Sulconazole

    go.drugbank.com/drugs/DB06820
    Approved

    [L44592,L44597] Sulconazole appears to be effective and well-tolerated in the treatment of superficial fungal infections.[A255612]

  3. Drug

    Tamsulosin

    go.drugbank.com/drugs/DB00706
    ApprovedInvestigational

    [Label] Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor muscles in the bladder, allowing for better urinary flow. … [Label] Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension.

    Products: TAMSULOSIN DOC GENERICI, TAMSULOSIN MYLAN GENERICS
  4. Drug

    Atosiban

    go.drugbank.com/drugs/DB09059
    ApprovedInvestigational

    It is used intravenously to halt premature labor. Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form. … Atosiban is licensed in proprietary and generic forms for the delay of imminent pre-term birth in pregnant adult women.

  5. Drug

    Ketobemidone

    go.drugbank.com/drugs/DB06738
    Investigational

    This makes it useful for some types of pain that don't respond well to other opioids. … The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  6. Drug

    Encainide

    go.drugbank.com/drugs/DB01228
    ApprovedWithdrawn

    Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack.

  7. Drug

    Thiodigalactoside

    go.drugbank.com/drugs/DB04396
    Experimental

    This compound belongs to the dihexoses. These are disaccharides containing two hexose carbohydrates. … This medication is known to target galectin-1, heat-labile enterotoxin b chain, neurocan core protein, and lactose permease.

  8. Drug

    Mefenamic acid

    go.drugbank.com/drugs/DB00784
    Approved

    A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.

  9. Drug

    PEV3A

    go.drugbank.com/drugs/DB05144
    Investigational

    The elicited antibodies are highly specific and able to inhibit the parasite’s ability to invade liver tissue _in vitro_. … It is a two-component vaccine that contains the virosome formulated peptide mimetics PEV301 and PEV302.

  10. Drug

    Ceforanide

    go.drugbank.com/drugs/DB00923
    Approved

    Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. … Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species

    Synonyms: 7-[O-(aminomethyl)phenylacetamido]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-3-cephem-4-carboxylic acid