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Efavaleukin alfa
go.drugbank.com/drugs/DB16149InvestigationalEfavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Synonyms: Fc il-2 mutein fusion protein (amg-592), Immunoglobulin g1 (fc domain-containing fragment) fusion protein with peptide (synthetic linker) fusion protein with interleukin 2 (synthetic human mutein), dimerEltanexor
go.drugbank.com/drugs/DB16153InvestigationalEltanexor is under investigation in clinical trial NCT02649790 (Study of the Safety, Tolerability and Efficacy of KPT-8602 in Patients With Relapsed/refractory Cancer Indications).
Categories: Heterocyclic Compounds, 1-RingEluforsen
go.drugbank.com/drugs/DB16154InvestigationalEluforsen is under investigation in clinical trial NCT02532764 (Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients).
Empegfilgrastim
go.drugbank.com/drugs/DB16155InvestigationalEmpegfilgrastim is under investigation in clinical trial NCT01569087 (Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer).
Epafipase
go.drugbank.com/drugs/DB16158InvestigationalEpafipase is under investigation in clinical trial NCT00037687 (Safety and Efficacy of Recombinant Human Platelet-activating Factor Acetylhydrolase for the Treatment of Severe Sepsis).
Fasoracetam
go.drugbank.com/drugs/DB16163InvestigationalFasoracetam is under investigation in clinical trial NCT03609619 (PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without Mglur Mutations).
Categories: Heterocyclic Compounds, 1-RingForalumab
go.drugbank.com/drugs/DB16170InvestigationalForalumab is under investigation in clinical trial NCT03291249 (Assessment of the Safety of Foralumab, an Oral Anti-cd3 Antibody, in Patients With NASH and T2DM).
Foslinanib
go.drugbank.com/drugs/DB16172InvestigationalFoslinanib is under investigation in clinical trial NCT03600233 (Study of CVM-1118 for Patients With Advanced Neuroendocrine Tumors).
Hemoporfin
go.drugbank.com/drugs/DB16183InvestigationalHemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsIfidancitinib
go.drugbank.com/drugs/DB16191InvestigationalIfidancitinib is under investigation in clinical trial NCT03585296 (A Study of ATI-502 Topical Solution for the Treatment of Atopic Dermatitis).