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Fucoxanthin
go.drugbank.com/drugs/DB15462Investigational, but the exact mechanism of anti-cancer action of fucoxanthin is not fully elucidated. … Fucoxanthin regulates lipids metabolism, the effect most likely mediated by AMK-activated protein kinase. A clinical trial of fucoxanthin against non-alcoholic fatty liver disease is ongoing.
Sotatercept
go.drugbank.com/drugs/DB12118ApprovedInvestigational[A263481] Sotatercept was approved by the European Commission on August 26, 2024.[L51549] … [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension (PAH).
Agkistrodon piscivorus antivenin
go.drugbank.com/drugs/DB13894ApprovedApproximately 99% of all venomous snake bites in the United States are caused by Crotalidae, also known as _pit vipers_. … The final purified antivenin product is obtained by mixing other different monospecific snake antivenins and isolating the antivenin of interest through fractionation and chromatography techniques.
Sulodexide
go.drugbank.com/drugs/DB06271ApprovedInvestigationalWithdrawnSulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).
Methyprylon
go.drugbank.com/drugs/DB01107ApprovedIllicitWithdrawnHowever, with the introduction of newer drugs with fewer side effects, such as benzodiazepines, the clinical use of methyprylon is now limited.
Dordaviprone
go.drugbank.com/drugs/DB14844ApprovedInvestigationalOn August 6, 2025, dordaviprone was granted accelerated approval by the FDA.[L53838] It is used to treat patients with diffuse midline glioma harboring an H3 K27M mutation.
Ceftiofur
go.drugbank.com/drugs/DB11485ExperimentalVet approvedIt is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. … Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine.
Zanidatamab zovodotin
go.drugbank.com/drugs/DB15472ExperimentalAccording to Zymeworks, "ZW49 (zanidatamab zovodotin) is a bispecific anti-HER2 ADC that is based on the same antibody framework as [ZW25] but armed with a cytotoxic payload." … [L8234] It is being investigated for several indications characterized by HER2 expression including breast and gastric cancers that have progressed or are refractory to existing HER2-targeted therapies
Urofollitropin
go.drugbank.com/drugs/DB00094ApprovedVet approvedWithdrawnIt consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. … Urofollitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF).