Urofollitropin is a form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure. Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified from human urine samples.
- Mechanism
- Curator reviewed
FSH binds to the follicle stimulating hormone receptor which is a G-coupled transmembrane receptor. Binding of the FSH to its receptor seems to induce phosphorylation and activation of the PI3K (Phosphatidylinositol-3-kinase) and Akt signaling pathway, which is known to regulate many other metabolic and related survival/maturation functions in cells.
- Primary indication
- For treatment of female infertilityCurator reviewed · 2 structured indications
- Formula / weight
- C42H65N11O12S2 · 980.162 Da
- First approval
- Canada, 2000
- Also known as
- Follitropin human · Urofollitrophin
Resolves to
What you can answer from here — as of September 14, 2026
Which drugs share a target with Urofollitropin, and which of those have an active Phase 3 trial?
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