Search

Displaying results 3121 - 3130 of 10000 in total

Drug
Dimazole
go.drugbank.com/drugs/DB13858
ApprovedWithdrawn
Dimazole (diamthazole) is an antifungal. It was withdrawn in Franch in 1972 due to neuropsychiatric reactions.
Categories: Antifungals for Topical Use, Antifungals for Dermatological Use
Drug
GC-376 free acid
go.drugbank.com/drugs/DB15796
Experimental
GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells … In addition, GC-376 displays potent activity against various coronaviruses such as feline, ferret, and mink Mpro coronavirus[A219026,A219031,A219036,A219041].
Categories: Experimental Unapproved Treatments for COVID-19
Drug
Meningococcal polysaccharide vaccine group A
go.drugbank.com/drugs/DB13889
ApprovedInvestigational
*N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. … It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup A.
Mixtures: Menomune-A/c/y/w-135, Menomune-A/c/y/w-135Synonyms: Neisseria meningitidis group A polysaccharide antigen, A, Meningococcal group A polysaccharide
Indication
Vision Disorders
go.drugbank.com/conditions/DBCOND0035879
Drugs: Almitrine · Faricimab · Ranibizumab
Synonyms: Poor vision
Drug
Gabapentin enacarbil
go.drugbank.com/drugs/DB08872
Approved
It is a prodrug of gabapentin, and indicated in adults for the treatment of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).
Drug
Idarubicin
go.drugbank.com/drugs/DB01177
ApprovedInvestigational
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexSynonyms: (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside
Drug
Zuranolone
go.drugbank.com/drugs/DB15490
ApprovedInvestigational
[A260791] Zuranolone was approved by the FDA on August 4th, 2023, and it is currently the only approved treatment for women with postpartum depression. … binding to a non-benzodiazepine site on the receptor.
Categories: Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator
Drug
Dihydroergocornine
go.drugbank.com/drugs/DB11273
Approved
[A32965] Dihydroergocornine presents a formula of 9,10 alpha-dihydro-12'-hydroxy-2',5'alpha-bis(1-methylethyl)-ergotaman-3',6',18-trione. … [A32962] It is an artificial derivative of the crude extract of ergot and later purified, ergocornine.
Categories: Heterocyclic Compounds with 4 or More Rings
Drug
Gadopiclenol
go.drugbank.com/drugs/DB17084
ApprovedInvestigational
Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. … It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body.
Drug
Carfentanil
go.drugbank.com/drugs/DB01535
IllicitInvestigationalVet approved
It is marketed under the trade name Wildnil as a general anaesthetic agent for large animals. … Carfentanil was first synthesized in 1974 by a team of chemists at Janssen Pharmaceutica which included Paul Janssen.