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Probucol
go.drugbank.com/drugs/DB01599ApprovedInvestigationalWithdrawnA drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Categories: Compounds used in a research, industrial, or household settingSynonyms: Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptoleMitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigationalTract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries. … [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Mito-C, Mitocin-CNiraparib
go.drugbank.com/drugs/DB11793ApprovedInvestigational[A253248] First approved by the FDA on March 27, 2017,[A253912] niraparib is used to treat epithelial ovarian, fallopian tube, or primary peritoneal cancer. … [L43277] Niraparib was approved by the European Commission on November 16, 2017 [L43742] and by Health Canada on June 27, 2019.
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic IndexAspergillus repens
go.drugbank.com/drugs/DB10449ApprovedAspergillus repens is a fungus which can provoke allergic reactions. Aspergillus repens extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureZolpidem
go.drugbank.com/drugs/DB00425ApprovedInvestigationalZolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. … Its tolerability profile is favorable when administered according to the manufacturer’s instructions, with a low risk of drug withdrawal, drug dependence, and drug tolerance [A175426].
Mixtures: Gabazolpidem-5, Sentrazolpidem PM-5Categories: GABA-A Receptor Agonists, Cytochrome P-450 SubstratesPiracetam
go.drugbank.com/drugs/DB09210ApprovedWithdrawnIt shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). … Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide.
Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingProducts: PIRACETAM-NEURAX M BESTECK, SETROPİL 1 G/ 5 ML İ.V. ÇÖZELTİ İÇEREN AMPUL, 12 ADETSebelipase alfa
go.drugbank.com/drugs/DB11563ApprovedInvestigationalThe lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs … [L39337] Sebelipase alfa is a recombinant form LAL approved for the treatment of LAL deficiency.
Products: KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION.Influenza B virus B/Darwin/7/2019 antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB15709ApprovedWithdrawnA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus
Synonyms: Influenza B virus B/Darwin/7/2019 antigen (MDCK cell derived, propiolactone inactivated)Mechlorethamine
go.drugbank.com/drugs/DB00888ApprovedInvestigationalA vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. … The FDA granted marketing approval for the orphan drug Valchlor (mechlorethamine) gel on August 23, 2013 for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL
Categories: Compounds used in a research, industrial, or household settingSynonyms: β,β'-dichlorodiethyl-N-methylamine, N-methyl-bis(2-chloroethyl)amineEnprofylline
go.drugbank.com/drugs/DB00824ApprovedWithdrawnEnprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. … Enprofylline is a derivative of theophylline which shares bronchodilator properties.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3-n-propylxanthine, 3-propylxanthine