Enprofylline is a derivative of theophylline which shares bronchodilator properties. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and... Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable blood levels.
- Mechanism
- Curator reviewed
Enprofylline inhibits erythrocyte phosphodiesterase, resulting in an increase in erythrocyte cAMP activity. Subsequently, the erythrocyte membrane becomes more resistant to deformity. Along with erythrocyte activity, enprofylline also decreases blood viscosity by reducing plasma fibrinogen concentrations and increasing fibrinolytic activity.
- Primary indication
- Used in the management of symptoms of asthma.Curator reviewed
- Formula / weight
- C8H10N4O2 · 194.1906 g/mol (avg)
- Also known as
- 3-n-propylxanthine · 3-propylxanthine
- Code names
- D-4028
Resolves to
SIQPXVQCUCHWDI-UHFFFAOYSA-NSMILESCCCN1C2=C(NC=N2)C(=O)NC1=OWhat you can answer from here — as of September 13, 2026
Which drugs share a target with Enprofylline, and which of those have an active Phase 3 trial?
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