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Displaying results 3121 - 3130 of 7059 in total
  1. Drug

    Pembrolizumab

    go.drugbank.com/drugs/DB09037
    ApprovedInvestigational

    It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. … [L38934,L43257] In September 2025, the US FDA approved a formulation of pembrolizumab that includes [berahyaluronidase alfa] (Keytruda QLEX) to allow for subcutaneous administration.[L54026]

  2. Drug

    Infigratinib

    go.drugbank.com/drugs/DB11886
    ApprovedInvestigationalWithdrawn

    cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) fusion or another rearrangement as detected by an FDA-approved test. … Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor.

  3. Drug

    Cemiplimab

    go.drugbank.com/drugs/DB14707
    ApprovedInvestigational

    Cemiplimab is a fully human monoclonal antibody that works against programmed death receptor-1 (PD-1), which is a negative regulator of T cell function. … [L39804] Cemiplimab was first approved by the FDA on September 28, 2018, as the first FDA-approved treatment for advanced cutaneous squamous cell carcinoma (CSCC).

  4. Drug

    Lumacaftor

    go.drugbank.com/drugs/DB09280
    ApprovedInvestigational

    [FDA Label] This data has been heavily scrutinized, however, with clinical trials showing only modest improvements despite a hefty yearly cost of $259,000 for Orkambi. … results in impaired production of the CFTR protein, thereby causing a significant reduction in the amount of ion transporter present on cell membranes.

  5. Drug

    Picafibrate

    go.drugbank.com/drugs/DB19574
    Experimental

    Picafibrate has a monoisotopic molecular weight of 362.1 Da. … Picafibrate is a small molecule drug.

  6. Drug

    Tiafibrate

    go.drugbank.com/drugs/DB19874
    Experimental

    Tiafibrate has a monoisotopic molecular weight of 686.23 Da. … Tiafibrate is a small molecule drug.

  7. Drug

    Iolopride I-123

    go.drugbank.com/drugs/DB20028
    Experimental

    Iolopride I-123 has a monoisotopic molecular weight of 400.06 Da. … Iolopride I-123 is a small molecule drug. The usage of the INN stem '-pride' in the name indicates that Iolopride I-123 is a sulpiride derivative and analogue.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Urefibrate

    go.drugbank.com/drugs/DB20849
    Experimental

    Urefibrate has a monoisotopic molecular weight of 354.02 Da. … Urefibrate is a small molecule drug.

  9. Drug

    Sitofibrate

    go.drugbank.com/drugs/DB21192
    Experimental

    Sitofibrate has a monoisotopic molecular weight of 610.42 Da. … Sitofibrate is a small molecule drug.

  10. Drug

    Ninerafaxstat

    go.drugbank.com/drugs/DB21486
    Investigational

    Ninerafaxstat has a monoisotopic molecular weight of 415.21 Da. … Ninerafaxstat is a small molecule drug.