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Displaying results 3151 - 3160 of 10000 in total
  1. Drug

    Alvespimycin

    go.drugbank.com/drugs/DB12442
    Investigational

    Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent.

  2. Drug

    Fidanacogene elaparvovec

    go.drugbank.com/drugs/DB16783
    ApprovedInvestigational

    from week 12 to month 15 compared to an ABR of 4.43 for the pre-treatment period. … Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human coagulation FIX gene that was investigated as a potential treatment for hemophilia B.

  3. Drug

    Pemigatinib

    go.drugbank.com/drugs/DB15102
    ApprovedInvestigational

    Pemigatinib is a small molecule kinase inhibitor with antitumour activity. … [A193719] FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide variety of cancers including those of the urinary bladder, breast

    Categories: MATE 1 Inhibitors, Cytochrome P-450 Substrates
  4. Drug

    Isoniazid

    go.drugbank.com/drugs/DB00951
    ApprovedInvestigational

    Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.

    Mixtures: RIP-PED, RINCURE ® 3 FDC TABLETAS CON PELICULACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  5. Drug

    Obinepitide

    go.drugbank.com/drugs/DB05045
    Experimental

    Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. … In obinepitide, the properties of both of these hormones have been implanted into a single molecule.

    Synonyms: (34-L-glutamine)pancreatic hormone (human)
  6. Drug

    Afimoxifene

    go.drugbank.com/drugs/DB04468
    Investigational

    Afimoxifene (4-Hydroxytamoxifen, trade name TamoGel) is a new estrogen inhibitor under investigation for a variety of estrogen-dependent conditions, including cyclic breast pain and gynecomastia. … This technology enables percutaneous delivery of drugs that cannot be delivered orally. It is being developed by Ascent Therapeutics.

    Synonyms: 4-OHT, 4-hydroxytamoxifen
  7. Drug

    Gallium chloride Ga-67

    go.drugbank.com/drugs/DB14550
    Approved

    Gallium chloride Ga-67 is the chloride salt of a gallium radioisotope which is typically complexed with [sodium citrate] to generate [gallium citrate Ga 67], which can be used to image certain cancers

    Synonyms: Gallium chloride Ga 67, Gallium chloride Ga-67Products: Gallium Citrate Ga-67
  8. Drug

    Maxy-G34

    go.drugbank.com/drugs/DB05718
    Investigational

    , while Neulasta has a single 20 Kd PEG group attached at the N terminal end of the wild type G-CSF protein. … MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF).

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Adakitug

    go.drugbank.com/drugs/DB05484
    Investigational

    MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation. … Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system.

    Synonyms: HuMax IL-8, HuMax-IL-8
  10. Drug

    Sebelipase alfa

    go.drugbank.com/drugs/DB11563
    ApprovedInvestigational

    [L39337] Sebelipase alfa is a recombinant form LAL approved for the treatment of LAL deficiency. … In addition, patients with LAL deficiency typically develop dyslipidemia, which itself contributes to a number of adverse cardiovascular outcomes.

    Products: KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION.