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Dasabuvir
go.drugbank.com/drugs/DB09183ApprovedDasabuvir is a non-nucleoside NS5B inhibitor which binds to the palm domain of NS5B and induces a conformational change which renders the polymerase unable to elongate viral RNA [FDA Label]. … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852].
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: Sodium 3-(3-tert-butyl-4-methoxy-5-{6 [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ide hydrate (1:1:1), N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamideIodixanol
go.drugbank.com/drugs/DB01249ApprovedIodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the
Mixtures: BL-C KitCategories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedZilganersen
go.drugbank.com/drugs/DB18161ApprovedInvestigationalZilganersen is a glial fibrillary acidic protein (GFAP)-directed antisense oligonucleotide used to treat Alexander disease. … [L64096] The FDA approved zilganersen on September 3, 2026 for the treatment of Alexander disease in pediatric and adult patients, making it the first and only disease-modifying treatment for the condition
Zomepirac
go.drugbank.com/drugs/DB04828ApprovedWithdrawnThe manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983. … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions.
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesSynonyms: 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acidAspergillus flavus
go.drugbank.com/drugs/DB10694ApprovedAspergillus flavus is a fungus which can provoke allergic reactions. Aspergillus flavus extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureEthanolamine oleate
go.drugbank.com/drugs/DB06689ApprovedIt is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate. … Ethanolamine oleate is a mild sclerosing agent.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Oleate de monoethanolamine, Oleato de monoetanolaminioLuliconazole
go.drugbank.com/drugs/DB08933ApprovedInvestigationalLuliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. … It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. Luliconazole is also approved in Japan.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A InhibitorsGaradacimab
go.drugbank.com/drugs/DB15629Approved[L53303,L53283] It is the first inhibitor of factor XIIa to receive market approval.[L53303] … [A273993] In June 2025, garadacimab was approved by the US FDA for the prophylaxis of HAE episodes in patients ≥12 years of age.
Landiolol
go.drugbank.com/drugs/DB12212ApprovedInvestigationalLandiolol is a rapid-acting beta (β)-1 adrenergic receptor blocker that blocks the positive chronotropic effect of the beta-1 selective agonist norepinephrine. … [A264733,A264738] First approved in Japan in 2002 [A264758] for the treatment of intraoperative tachyarrhythmias,[A264733] landiolol was approved in Canada in April 2024 [L51938] and in the US in November
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-(4-{(2S)-2-hydroxy-3-[{2-[(morpholin-4-ylcarbonyl)amino]ethyl}amino]propoxy}phenyl)propanoate, (-)-2,2-dimethyl-1,3-dioxolan-4S-ylmethyl 3-[4-[3-[2-(morpholinocarbonylamino)ethylamino]-2S-hydroxypropoxy]phenyl]propionatePenicillium camemberti
go.drugbank.com/drugs/DB10809ApprovedPenicillium camemberti is a fungus which can provoke allergic reactions. Penicillium camemberti extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture