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Lindane
go.drugbank.com/drugs/DB00431ApprovedWithdrawnAn organochlorine insecticide that has been used as a pediculicide and a scabicide. … In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical
Categories: Compounds used in a research, industrial, or household settingEtranacogene dezaparvovec
go.drugbank.com/drugs/DB16791ApprovedInvestigationalThe therapy involves a one-time infusion of a viral vector carrying a codon-optimized DNA sequence of the gain-of-function Padua variant of human Factor IX controlled by a liver-specific promotor 1. … Hemophilia B - also called factor IX deficiency or Christmas disease - is an X-linked genetic disorder resulting in an absence or deficiency of clotting factor IX.
Toripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigationalThe proliferation of some cancers can be attributed, at least in part, to the suppression of host tumor surveillance. … [L48681] Toripalimab is a selective, recombinant, humanized IgG4 monoclonal antibody targeted against the PD-1 receptor.
Tenecteplase
go.drugbank.com/drugs/DB00031ApprovedInvestigationalIt is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids … Tenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA).
Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen
go.drugbank.com/drugs/DB10799ApprovedInvestigationalNeisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria
Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen
go.drugbank.com/drugs/DB10800ApprovedInvestigationalNeisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria
Reviparin
go.drugbank.com/drugs/DB09259ApprovedReviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. … Reviparin has a molecular weight of 3.9 kDa.[A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation by the FDA.[L1469]
Products: CLIVARIN 5726 IE A XA/ML, CLIVARODI 17178 A XA/MLQR-334
go.drugbank.com/drugs/DB05473ExperimentalSialorrhea is an excess secretion of saliva produced by the salivary glands, resulting in drooling. No pharmaceutical interventions currently exist to treat sialorrhea. … The symptom is associated with many diseases including Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s Disease, Cerebral Palsy, Parkinson's Disease, and Muscular Dystrophy.
Netilmicin
go.drugbank.com/drugs/DB00955ApprovedNetilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexHalofantrine
go.drugbank.com/drugs/DB01218ApprovedWithdrawnHalofantrine is an antimalarial. It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine.
Products: Halfan - Tab 250mg