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Displaying results 3171 - 3180 of 8698 in total
  1. Drug

    Tirbanibulin

    go.drugbank.com/drugs/DB06137
    ApprovedInvestigational

    [L27806] Actinic keratosis is a chronic condition characterized by lesions, which can potentially transform into invasive squamous cell carcinoma with a risk of 1% over 10 years. … [A225726] On December 14, 2020, tirbanibulin was approved by the FDA for the topical treatment of actinic keratosis on the face or scalp. It is marketed under the brand name Klisyri.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  2. Drug

    Oxycodegol

    go.drugbank.com/drugs/DB14146
    Investigational

    Nektar Therapeutics has filed an application for FDA approval of Loxicodegol for use in the treatment of chronic lower back pain [L3263] … Loxicodegol was developed by Nektar Therapeutics as an opioid analgesic with low abuse potential for the treatment of chronic pain [L3263].

  3. Drug

    Monobenzone

    go.drugbank.com/drugs/DB00600
    ApprovedWithdrawn

    It may also cause destruction of melanocytes and permanent depigmentation. … Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation.

    Synonyms: p-(Benzyloxy)phenol, Benzyl p-hydroxyphenyl ether
  4. Drug

    Trichophyton rubrum

    go.drugbank.com/drugs/DB10915
    Approved

    Trichophyton rubrum is a fungus which can provoke allergic reactions. Trichophyton rubrum extract is used in allergenic testing.

    Mixtures: Trichophyton for Intradermal Skin Testing
  5. Drug

    Vardenafil

    go.drugbank.com/drugs/DB00862
    Approved

    Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction. … Compared to [sildenafil] and [tadalafil], vardenafil is a more potent inhibitor of PDE5; however, its selectivity for other PDE isoforms is lower than the one detected for tadalafil.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  6. Drug

    Amphetamine

    go.drugbank.com/drugs/DB00182
    ApprovedIllicitInvestigational

    It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted.

    Categories: Psychostimulants, Agents Used for ADHD and Nootropics, Cytochrome P-450 Substrates
  7. Drug

    Bisoxatin

    go.drugbank.com/drugs/DB09219
    Approved

    It is marketed in Belgium under the tradename Wylaxine and used for the treatment of constipation and for preparation of the colon for surgical procedures.

    Categories: Drugs for Constipation
  8. Indication

    Silent Miscarriage

    go.drugbank.com/conditions/DBCOND0170985
    Drugs: Misoprostol
    Synonyms: MA - Missed abortion
  9. Drug

    Phenaridine

    go.drugbank.com/drugs/DB09178
    ExperimentalIllicit

    Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue … It was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl. In rat studies, it was less potent than fentanyl.

  10. Drug

    Ziconotide

    go.drugbank.com/drugs/DB06283
    ApprovedInvestigational

    [L13389] To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA.[A202835] … [A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because it can be

    Categories: N-Calcium Channel Receptor Antagonists