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Displaying results 3181 - 3190 of 10000 in total
  1. Drug

    Remlarsen

    go.drugbank.com/drugs/DB19131
    Investigational

    Remlarsen is under investigation in clinical trial NCT03601052 (Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids).

    Synonyms: -cholest-5-en-3-yloxy)hexyl)oxy)-2-hydroxypropyl hydrogen phosphate), complex with rna ((2'-deoxy-2'-fluoro)u-a-g-(2'-deoxy-2'-fluoro)c-a-(2'-deoxy-2'-fluoro)c-(2'-de, Rna, (am-am-cm-a-cm-um-g-um-um-um-a-cm-a-a-a-um-g-g-um-cm-cm-um-a), 3'-(3-((6-((3.beta.)
  2. Drug

    Iron Dextran

    go.drugbank.com/drugs/DB00893
    ApprovedInvestigationalVet approved

    Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use.

    Mixtures: Irospan 24/6Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Atogepant

    go.drugbank.com/drugs/DB16098
    ApprovedInvestigational

    [A239094] The "gepants" family of drugs, including atogepant, are comparatively well-tolerated[A189207,L38739] and may provide a desirable treatment option for patients struggling with adverse reactions

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: AQUIPTA® 10 MG, AQUIPTA® 60 MG
  4. Drug

    Drospirenone

    go.drugbank.com/drugs/DB01395
    ApprovedInvestigational

    Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with [Ethinyl estradiol]. … Some studies have demonstrated a significantly increased risk and some demonstrating no risk of thromboembolic events.

    Mixtures: VERONIQ ® 3 MG / 30 MCG, VERONIQ® 3 MG / 30 MCGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    KB3305

    go.drugbank.com/drugs/DB06349
    Experimental

    KB3305 is an investigational liver selective antagonist for the glucocorticoid receptor, developed by Karo Bio for the treatment of Type 2 Diabetes.

    Categories: 17-KetosteroidsSynonyms: 3.BETA.,5.BETA.,7.ALPHA.,12.ALPHA.)-7,12-DIHYDROXY-3-(2-((4-((11.BETA.,17.BETA.)-17-HYDROXY-3-OXO-17-(1-PROPYN-1-YL)ESTRA-4,9-DIEN-11-YL)PHENYL)METHYLAMINO)ETHOXY)CHOLAN-24-OIC ACID, CHOLAN-24-OIC ACID, 7,12-DIHYDROXY-3-(2-((4-((11.BETA.,17.BETA.)-17-HYDROXY-3-OXO-17-(1-PROPYN-1-YL)ESTRA-4,9-DIEN-11-YL)PHENYL)METHYLAMINO)ETHOXY)-, (3.BETA.,5.BETA.,7.ALPHA.,12.ALPHA.)-
  6. Drug

    Verteporfin

    go.drugbank.com/drugs/DB00460
    ApprovedInvestigational

    Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: [CL-315555] and [CL-315585]. … It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsProducts: VISUDYNE FOR INJECTION 15 mg/vial, VISUDYNE 15 MG INFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ
  7. Drug

    Fibrinogen human

    go.drugbank.com/drugs/DB09222
    ApprovedInvestigational

    Fibrinogen concentrate (human) is a hematological agent. It works by replacing a specific protein in the blood, fibrinogen (factor I), that helps with blood clotting. … It is a soluble plasma glycoprotein with a molecular weight of about 340 kDa and is a physiological substrate for three enzymes: plasmin, factor XIIIa, and thrombin.

    Mixtures: EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml, BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICISynonyms: Factor I human, Coagulation Factor I
  8. Drug

    Mineral oil

    go.drugbank.com/drugs/DB11057
    ApprovedInvestigationalVet approved

    Unrefined or mildly treated mineral oils are classified as Group 3 carcinogens by the World Health Organizations, as chronic exposure to these aromatics including alkylated polycyclic aromatic compounds … Mineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum.

    Mixtures: 7 Select Hemorrhoidal Original Strength, AGAROL M (EMULSION)Products: LIQUID PARAFFIN EMULSION 2.5 ml/5 ml, LAXAROL ORAL EMULSION 50% v/v
  9. Drug

    Calcium

    go.drugbank.com/drugs/DB01373
    ApprovedInvestigationalNutraceutical

    Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. … Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate.

    Mixtures: CALCIDAY G 1200 MG/800 IU/50 MG EFERVESAN TABLET, 45 ADET, OSMEGA 600 MG/400 IU/25 MG EFERVESAN TABLET, 30 ADETCategories: ascorbic acid (vit C) and calcium
  10. Drug

    Remdesivir

    go.drugbank.com/drugs/DB14761
    ApprovedInvestigational

    [L18438] Remdesivir was also approved by the European Commission on July 3, 2020. … Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: VEKLURY 100 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET, VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIAL