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Displaying results 311 - 320 of 10000 in total
  1. Drug

    Hydroxychloroquine

    go.drugbank.com/drugs/DB01611
    ApprovedInvestigational

    [L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546] … Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine].

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol
  2. Drug

    Omega-6 fatty acids

    go.drugbank.com/drugs/DB13168
    InvestigationalNutraceutical

    Cells involved in the inflammatory response are typically rich in the n-6 fatty acid arachidonic acid, as generally, eicosanoids derived from n-6 PUFA are pro-inflammatory. … Omega-6 fatty acids are polyunsaturated fatty acids with a final carbon-carbon double bond in the n-6 position, that is, the sixth bond, counting from the methyl end.

    Synonyms: n-6 fatty acids, ω-6 fatty acids
  3. Drug

    Fenbufen

    go.drugbank.com/drugs/DB08981
    Approved

    Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. … Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast.

    Categories: Non COX-2 selective NSAIDSSynonyms: 4-(4-Biphenylyl)-4-oxobutyric acid, 3-(4-Phenylbenzoyl)propionic acid
  4. Drug

    Apomorphine

    go.drugbank.com/drugs/DB00714
    ApprovedInvestigational

    Apomorphine is a non-ergoline dopamine D2 agonist indicated to treat hypomobility associated with Parkinson's. It was first synthesized in 1845 and first used in Parkinson's disease in 1884. … [A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.

    Categories: Heterocyclic Compounds with 4 or More Rings, Drugs Used in Erectile DysfunctionSynonyms: (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
  5. Drug

    1-Benzyl-3-(4-Methoxy-Benzenesulfonyl)-6-Oxo-Hexahydro-Pyrimidine-4-Carboxylic Acid Hydroxyamide

    go.drugbank.com/drugs/DB04140
    Experimental

    Synonyms: 1-Benzyl-3-(4-Methoxy-Benzenesulfonyl)-6-Oxo-Hexahydro-Pyrimidine-4-Carboxylic Acid Hydroxyamide
  6. Drug

    4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE

    go.drugbank.com/drugs/DB07029
    Experimental

    Synonyms: 4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE
  7. Drug

    4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL

    go.drugbank.com/drugs/DB07100
    Experimental

    Synonyms: 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
  8. Drug

    Luvadaxistat

    go.drugbank.com/drugs/DB16067
    Investigational

    Luvadaxistat is under investigation in clinical trial NCT03214588 (Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia).

    Categories: D-Amino Acid Oxidase InhibitorSynonyms: 3(2H)-PYRIDAZINONE, 4-HYDROXY-6-(2-(4-(TRIFLUOROMETHYL)PHENYL)ETHYL)-, 4-HYDROXY-6-(2-(4-(TRIFLUOROMETHYL)PHENYL)ETHYL)-2,3-DIHYDROPYRIDAZIN-3-ONE
  9. Drug

    Sulfur hexafluoride

    go.drugbank.com/drugs/DB11104
    ApprovedInvestigational

    in adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric patients … Sulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border

    Synonyms: sulfur(6+) fluorideProducts: SONOVUE POWDER FOR DISPERSION FOR INJECTION 8 microlitres/ml
  10. Drug

    Pramipexole

    go.drugbank.com/drugs/DB00413
    ApprovedInvestigational

    Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). … Parkinson's Disease is one of the most common neurodegenerative disorders and causes a high level of disability in patients [A176855], leading to increased difficulty in performing activities of daily

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (S)-N  6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine