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Fedratinib
go.drugbank.com/drugs/DB12500ApprovedInvestigationalFedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: Inrebic 100 mg capsules, Inrebic 100 mg Sert Kapsül, 120 ADETPhenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalAccording to the European Union Cosmetics Regulation (EC) n.1223/2009, phenoxyethanol is authorized as a preservative in cosmetic formulations at a maximum concentration of 1.0% [L2625]. … Phenoxyethanol is a colorless liquid with a pleasant odor.
Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, OCTENISEPT ÇÖZELTI, 50 MLProducts: Lanohex Nettoyeur Pour LA Peau 1.7%Baclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalBaclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.
Products: BACLOFEN AL 25MG TABLETTEN, COLMIFEN 10 TABLET 10 mgMilrinone
go.drugbank.com/drugs/DB00235ApprovedInvestigationalHeart failure is a multifactorial condition that affects roughly 1-2% of the adult population. … [A228323] Milrinone is a second-generation bipyridine phosphodiesterase (PDE) inhibitor created through chemical modification of [amrinone].
Categories: Compounds used in a research, industrial, or household settingProducts: MILRINONA 10 MG/10 ML, MILRINONA 10 MG/ 10 MLFurosemide
go.drugbank.com/drugs/DB00695ApprovedInvestigationalVet approved[A182495] The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. … Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative.
Mixtures: Lasilacton 20 mg/100 mg Kapseln, Lasilacton 20 mg/50 mg KapselnProducts: FUROSEMID 250 1A PHARMA, Furosemid 1A Pharma 40 mg - TablettenAcitretin
go.drugbank.com/drugs/DB00459ApprovedInvestigationalIt is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Products: Keracutan 10 mg Kapseln, NEOTIGASON 10 MG KAPSUL, 100 ADETCodeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalCodeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities.
Mixtures: A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 20 ADET, A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 500 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigationalPentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties. … A branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant Pharmaceuticals and APOTEX have been available since the late 1990s.[L30300]
International brands: Ao Le NiCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesDurvalumab
go.drugbank.com/drugs/DB11714ApprovedInvestigationalDurvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. … [A192789] Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture,[L12621] durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: IMFINZI CONCENTRATE FOR SOLUTION FOR INFUSION 50 MG/ML, IMFINZI 120 MG/2.4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETPamidronic acid
go.drugbank.com/drugs/DB00282ApprovedInvestigationalPamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and [alendronic acid].[A203111] Pamidronic acid was first described in the literature in 1977.
Products: MENEDRON-L 15 MG IV ENJEKSİYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON (4 FLAKON), Pamitor 15 mg/ml - Konzentrat zur Herstellung einer Infusionslösung