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Rurioctocog alfa pegol
go.drugbank.com/drugs/DB16007ApprovedInvestigationalIt was first approved by the European Commission in January 2018.
Trypsin
go.drugbank.com/drugs/DB11237ApprovedInvestigationalVet approvedWhen converted from its zymogen trypsinogen, trypsin is available as an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at the carboxyl side of the amino acids lysine or arginine
Avacincaptad pegol
go.drugbank.com/drugs/DB15165ApprovedInvestigationalIt was developed to treat an advanced form of age-related macular degeneration (AMD) called geographic atrophy (GA). … AMD eventually progresses to bilateral and irreversible loss of vision, whether or not the patients have the non-neovascular (dry) or the neovascular (wet) form of AMD.
Zolazepam
go.drugbank.com/drugs/DB11555ExperimentalVet approvedIt is around four times the potency of diazepam but it is both water-soluble and un-ionized at physiological pH meaning that its onset is very fast.
Prolectin-M
go.drugbank.com/drugs/DB16521Investigational[L31343] It is being investigated in the clinical trial NCT04512027 (Prolectin-M in COVID-19 Patients Having Mild to Moderate Symptoms Not Requiring Oxygen Support. (Prolectin-M)).
Insulin detemir
go.drugbank.com/drugs/DB01307ApprovedInvestigational[A2358, A2359, A2360, A44] This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine amino acid at position B29. … [A2358, A2359, A2360, A44] Marketed as the brand name product Levemir, insulin detemir has a duration of action of 16-24 hours allowing for once-daily dosing, typically at bedtime.
Propanoic acid
go.drugbank.com/drugs/DB03766ApprovedInvestigationalVet approvedWithdrawnIt is considered generally recognized as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and flavoring agent.
AT2220
go.drugbank.com/drugs/DB05200InvestigationalGAA to the lysosome, where it can perform its normal function. … It is a small molecule designed to act as a pharmacological chaperone that specifically binds, stabilizes, and facilitates the proper folding and trafficking of α-glucosidase (GAA).
Benmoxin
go.drugbank.com/drugs/DB09246ApprovedWithdrawnIt was first synthesized in 1967 and rapidly used in Europe as an antidepressant. However, this agent is no longer marketed.