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Ferric derisomaltose
go.drugbank.com/drugs/DB15617ApprovedInvestigational[A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. This drug is a complex of iron (III) hydroxide and derisomaltose. … The latter is an iron carbohydrate oligosaccharide that works to release iron. Ferric derisomaltose was developed by Pharmacosmos Therapeutics ad was granted FDA approval in January 2020.
Products: Diafer 50 mg/ml Injektionslösung, MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/MLLetermovir
go.drugbank.com/drugs/DB12070ApprovedInvestigationalLetermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. … [L1021] It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors.[A31290] Letermovir has recieved both priority and orphan drug status from the FDA.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: PREVYMİS 240 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, PREVYMİS 480 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETImatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigationalBrian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy". … Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluididePeginterferon beta-1a
go.drugbank.com/drugs/DB09122ApprovedInvestigationalMultiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. … [L5801] MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.
Mixtures: Plegridy Pen, Plegridy PenCategories: Compounds used in a research, industrial, or household setting, Interferon Type IBurosumab
go.drugbank.com/drugs/DB14012ApprovedInvestigationalX-linked hypophosphatemia causes low circulating levels of phosphorus in the blood. … Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic
Products: CRYSVITA® SOLUCIÓN PARA INYECCIÓN 20 MG/ML, CRYSVITA® SOLUTION FOR INJECTION 10 MG/MLDenosumab
go.drugbank.com/drugs/DB06643ApprovedInvestigationalTwo denosumab biosimilars—Wyost® (denosumab-bbdz) [L53063] and Jubbonti® (denosumab-bbdz)[L53058]—were approved by the FDA in March 2024 for all indications of the reference products Xgeva® and Prolia® … ; Both biosimilars also received marketing authorization in the EU in May 2024.
Products: XGEVA® 120 MG/1.7 ML, XGEVA 120 MG SC. ENJEKSIYONLUK COZELTI ICEREN FLAKON, 4 ADETRubella virus vaccine
go.drugbank.com/drugs/DB10317ApprovedInvestigationalIt is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus). … Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered.
Synonyms: Rubella virus live antigen, A, Rubella virus (vaccine strain RA27/3) live antigenMixtures: Priorix Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung einer Injektionslösung, Priorix - Tetra Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung einer InjektionslösungEsmolol
go.drugbank.com/drugs/DB00187ApprovedInvestigationalWithdrawnEsmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate of heart contractions.
Synonyms: Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate, 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl esterCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalIt is available as an extended-release tablet, a once-monthly intramuscular injection, an every-three-month intramuscular injection, and a twice-yearly gluteal injection.[L16168,L37744,L4137,L37749] … It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism.
Synonyms: 9-hydroxyrisperidoneCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsTrazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigational[T646] Trazodone acts on various receptors, including certain histamine, serotonin, and adrenergic receptors, distinguishing it from other antidepressants that cover a narrow range of neurotransmitters … receptor inhibitor (SNRIs) in the treatment of depression.
Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsSynonyms: 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one