Search
Frizzled-5
go.drugbank.com/bio_entities/BE0014104TargetHumansReceptor for Wnt proteins (PubMed:10097073, PubMed:20530549, PubMed:26908622, PubMed:9054360). Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling (By sim...
Polypeptides: Frizzled-5Synonyms: Fz-5Dabocemagene autoficel
go.drugbank.com/drugs/DB17878InvestigationalDabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene a...
Synonyms: AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING, SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER, -HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND 3'-LTR/POMizolastine
go.drugbank.com/drugs/DB12523ApprovedMizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2D6 InhibitorsProducts: MIZOLEN 10 MG TABLETAS DE LIBERACION PROLONGADAAprotinin
go.drugbank.com/drugs/DB06692ApprovedInvestigationalWithdrawnAprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI). … The goal of using of aprotinin was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and to reduce the necessity for blood transfusions during surgery.
Mixtures: Tisseel Lyo - Pulver und Lösungsmittel für einen Gewebekleber, ARTISS 10 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTOR, 1 ADETCategories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsEribulin
go.drugbank.com/drugs/DB08871ApprovedInvestigationalEribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic
Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsProducts: HALAVEN 0.5 mg/ml solution for injection, Eribulin Advanz Pharma 0,44 mg/ml InjektionslösungMaprotiline
go.drugbank.com/drugs/DB00934ApprovedMaprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). … Maprotiline may be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder.
Categories: Tricyclics and Other Norepinephrine-reuptake Inhibitors, Cytochrome P-450 SubstratesProducts: MAPROTILIN-NEURAX 50 MG, Ludiomil 50 mg - FilmtablettenFamciclovir
go.drugbank.com/drugs/DB00426ApprovedInvestigationalFamciclovir is a prodrug of penciclovir with higher oral bioavailability. … Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles).
Categories: Heterocyclic Compounds, 2-Ring, Nucleosides and NucleotidesSynonyms: 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetateProteasome subunit beta type-10
go.drugbank.com/bio_entities/BE0004738TargetHumansThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-depe...
Polypeptides: Proteasome subunit beta type-10Synonyms: Low molecular mass protein 10Keratin, type I cytoskeletal 10
go.drugbank.com/bio_entities/BE0009062TargetHumansStructural component of intermediate filaments in suprabasal keratinocytes of stratified epithelia. Forms heteropolymers primarily with the type II keratin KRT1, and also with KRT2, assembling into intermediate filament networks that sup...
Polypeptides: Keratin, type I cytoskeletal 10Synonyms: CK-10, Keratin-10Serine/threonine-protein kinase 10
go.drugbank.com/bio_entities/BE0009541TargetHumansSerine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a neg...
Polypeptides: Serine/threonine-protein kinase 10