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Displaying results 3211 - 3220 of 10000 in total
  1. Drug

    Temelimab

    go.drugbank.com/drugs/DB15634
    Investigational

    Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).

  2. Drug

    Omidubicel

    go.drugbank.com/drugs/DB17132
    ApprovedInvestigational

    [A258938,A258943,L46048] This type of cell therapy benefits patients that require stem cell transplantation as a treatment for blood cancers for whom a related or unrelated donor cannot be found due to … In addition, the fact that 39% of the study's cohort were non-White patients highlights the importance of this type of treatment in key demographics with low donor availability.

    Synonyms: Allogeneic, ex-vivo expanded, umbilical cord blood-derived hematopoietic CD34+ progenitor cells - cultured fraction (CF)
  3. Drug

    Vatalanib

    go.drugbank.com/drugs/DB04879
    Investigational

    Vatalanib (PTK787/ZK-222584) is a new oral antiangiogenic molecule that inhibits all known vascular endothelial growth factor receptors. Vatalanib is under investigation for the treatment of solid tumors.

  4. Drug

    Apararenone

    go.drugbank.com/drugs/DB15024
    Investigational

    Apararenone is under investigation in clinical trial NCT02531568 (Drug Interaction Study of Warfarin and MT-3995).

  5. Drug

    ATA-100

    go.drugbank.com/drugs/DB18329
    Investigational

    ATA-100 is an adeno-associated virus serotype 9 carrying the human Fukutin-Related protein gene and target sequence of the miR-208a

  6. Drug

    Mespirenone

    go.drugbank.com/drugs/DB20625
    Experimental

    The usage of the INN stem '-renone' in the name indicates that Mespirenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. … Mespirenone has a monoisotopic molecular weight of 426.19 Da.

  7. Drug

    Malathion

    go.drugbank.com/drugs/DB00772
    Approved

    Malathion is an irreversible cholinesterase inhibitor and has low human toxicity. … Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: O,O-dimethyl S-1,2-di(ethoxycarbamyl)ethyl
  8. Drug

    MK-1496

    go.drugbank.com/drugs/DB12763
    Investigational

    MK-1496 has been used in trials studying the treatment of Neoplasms and Malignant.

  9. Drug

    MK-5108

    go.drugbank.com/drugs/DB12556
    Investigational

    MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors.

  10. Drug

    Remoxipride

    go.drugbank.com/drugs/DB00409
    ApprovedWithdrawn

    Remoxipride is an atypical antipsychotic agent that is specific for dopamine D<sub>2</sub> receptors. … [A215422] It gained approval in the UK in 1989 but was withdrawn in 1993 after it was found to be associated with an increased incidence of aplastic anemia.[A215422,A215512]

    Categories: Dopamine D2 Receptor Antagonists