Search

Displaying results 3211 - 3220 of 10000 in total
  1. Drug

    Antihemophilic factor, human recombinant

    go.drugbank.com/drugs/DB00025
    ApprovedInvestigational

    Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells

    Categories: Hemophilia A
  2. Drug

    GTS-21

    go.drugbank.com/drugs/DB05708
    Investigational

    related and memory related tasks (Kitagawa, et al. … In a Phase I multi-dose, double-blind, placebo controlled study in healthy adults, GTS-21 also demonstrated cognitive enhancement across all doses, with a statistically significant improvement in attention

    Synonyms: DMXB-A
  3. Drug

    Zidebactam

    go.drugbank.com/drugs/DB13090
    Approved

    Zidebactam is a diazabicyclooctane that acts both as a beta-lactamase inhibitor and as an antibacterial in its own right, selectively binding penicillin-binding protein 2. … [L63350] It is available only in fixed combination with [cefepime], which binds PBP3 and PBP1a/b.

  4. Drug

    Andrographolide

    go.drugbank.com/drugs/DB05767
    Investigational

    Andrographolide (HMPL-004) is a botanical product extracted from a herb that occurs naturally in China. … The herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and other inflammatory and infectious diseases.

  5. Drug

    Amyl Nitrite

    go.drugbank.com/drugs/DB01612
    Approved

    Its use as a prescription medicine comes from its ability to lower blood pressure. As an inhalant, it also has psychoactive effect which has led to illegal drug use. … Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning.

    Synonyms: n-Amyl nitrite, n-pentyl nitrite
  6. Drug

    DOTMP HO-166

    go.drugbank.com/drugs/DB05380
    Experimental

    SRT is designed to be used in combination with high-dose chemotherapy producing a direct therapeutic effect on the tumor sites in the bone plus a general bone-marrow effect to destroy myeloma cells in … DOTMP HO-166 is used in skeletal targeted radiotherapy (STR).

  7. Drug

    Rose bengal I-131

    go.drugbank.com/drugs/DB09388
    Approved

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Cerulenin

    go.drugbank.com/drugs/DB01034
    Experimental

    In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. … It is also shown to inhibit feeding and induce dramatic weight loss in mice. It is found naturally in the Cephalosporium caerulensfungus.

  9. Drug

    Eluxadoline

    go.drugbank.com/drugs/DB09272
    ApprovedInvestigational

    Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). … of abdominal pain and reductions in the Bristol Stool Scale.

    Synonyms: 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acid
  10. Drug

    Plozalizumab

    go.drugbank.com/drugs/DB12520
    Investigational

    The recruitment of macrophages to the arterial wall is believed to be a critical step in the development of atherosclerosis. … Plozalizumab, a novel humanized monoclonal antibody, specifically targets CCR2 chemokine receptors found on the surface of certain white blood cells including macrophages and monocytes.