Amyl Nitrite is a fast acting vasodilator used for rapid relief of angina pectoris. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning.
- Mechanism
- Curator reviewed
Amyl nitrite's antianginal action is thought to be the result of a reduction in systemic and pulmonary arterial pressure (afterload) and decreased cardiac output because of peripheral vasodilation, rather than coronary artery dilation. Amyl nitrite is a source of nitric oxide, which accounts for the mechanism described above. As an antidote (to cyanide poisoning), amyl nitrite promotes formation of methemoglobin, which combines with cyanide to form nontoxic cyanmethemoglobin.
- Primary indication
- For the rapid relief of angina pectoris.Curator reviewed
- Formula / weight
- C5H11NO2 · 117.1463 g/mol (avg)
- First approval
- Canada, 2000
- Also known as
- 1-nitropentane · n-Amyl nitrite · n-pentyl nitrite · Nitramyl · pentyl nitrite
Resolves to
CSDTZUBPSYWZDX-UHFFFAOYSA-NSMILESCCCCCON=OWhat you can answer from here — as of September 12, 2026
Which drugs share a target with Amyl Nitrite, and which of those have an active Phase 3 trial?
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