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Thonzonium
go.drugbank.com/drugs/DB09552ApprovedThonzonium is a monocationic surface-active agent with surfactant and detergent properties. … A common pharmaceutical formulation of thonzonium bromide is cortisporin-TC ear drops. It is also reported that thonzonium also confers an antifungal property and antiresorptive effect on bone.
Mixtures: Coly-Mycin S, Coly-Mycin SCategories: Heterocyclic Compounds, 1-RingBufexamac
go.drugbank.com/drugs/DB13346ApprovedWithdrawnBufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. … The use of bufexamac has been discontinued in Canada and the United States, which may be due to undetermined clinical efficacy and a high prevalence of contact sensitization [A32822].
Synonyms: 4-Butoxy-N-hydroxybenzeneacetamide, 2-(p-Butoxyphenyl)-acetohydroxamic acidCategories: Non COX-2 selective NSAIDSInterferon alfa
go.drugbank.com/drugs/DB05258ApprovedInvestigationalWithdrawnInterferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. … Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus.
Synonyms: IFN-αCategories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsFlubendazole
go.drugbank.com/drugs/DB08974ApprovedInvestigationalWithdrawnFlubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Synonyms: methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate, (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl esterCategories: Heterocyclic Compounds, 2-RingColesevelam
go.drugbank.com/drugs/DB00930ApprovedInvestigationalColesevelam is a bile acid sequestrant. … Bile acids are made when cholesterol is broken down in the body. Removing these bile acids helps to lower blood cholesterol.
Delamanid
go.drugbank.com/drugs/DB11637ApprovedInvestigationalIt is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. … Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for patients, as the disease is associated with a higher mortality rate and insufficient therapeutic
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo[2,1-b]oxazole, (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo(2,1-B)(1,3)oxazoleMetipranolol
go.drugbank.com/drugs/DB01214ApprovedWithdrawnA beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Synonyms: Acetic acid 4-(2-hydroxy-3-isopropylamino-propoxy)-2,3,6-trimethyl-phenyl esterCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesTrimetrexate
go.drugbank.com/drugs/DB01157ApprovedA nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. … It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
Categories: Heterocyclic Compounds, 2-RingCefpirome
go.drugbank.com/drugs/DB13682ApprovedCefpirome is a β-lactam or cephalosporin.[A249055]
Categories: Heterocyclic Compounds, 2-RingHomatropine
go.drugbank.com/drugs/DB11181ApprovedHomatropine hydrobromide has been administered as ophthalmic solutions as a cycloplegic to temporarily paralyze accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic … Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors.
Products: HOMATRO 2%, Isopto Homatropine 2%