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Isopropamide
go.drugbank.com/drugs/DB01625ApprovedVet approvedWithdrawnIsopropamide iodide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.
Mixtures: Stelabid No 2, Stelabid No 1Etoricoxib
go.drugbank.com/drugs/DB01628ApprovedInvestigationalWithdrawnEtoricoxib is a new COX-2 selective inhibitor. … Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid.
Categories: COX-2 Inhibitors, Cytochrome P-450 SubstratesSynonyms: 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine, 5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinylSorbitol
go.drugbank.com/drugs/DB01638ApprovedInvestigationalIt was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. … A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose.
Mixtures: Cystosol W 3% Hexitols, INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion)Categories: Compounds used in a research, industrial, or household setting4-hydroxybenzoyl-CoA
go.drugbank.com/drugs/DB01652ExperimentalCategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-RingSynonyms: 4-hydroxybenzoyl coenzyme A, 4-hydroxybenzoyl-coenzyme ARoflumilast
go.drugbank.com/drugs/DB01656ApprovedInvestigationalRoflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor. … [A251385] PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme [L37564] expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: DAXAS®Methacrylyl-Coenzyme A
go.drugbank.com/drugs/DB01675ExperimentalCategories: Heterocyclic Compounds, 2-RingSynonyms: Methacrylyl-Coenzyme A(Rp)-cAMPS
go.drugbank.com/drugs/DB01790ExperimentalSynonyms: (Rp)-adenosine-3',5'-cyclic monophosphorothioate, adenosine-3',5'-cyclic monophosphorothioate, Rp-isomerCategories: Heterocyclic Compounds, 2-RingPiclamilast
go.drugbank.com/drugs/DB01791ExperimentalPiclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. … The structure for piclamilast was first elucidated in a 1995 European patent application and exhibits the structural functionalities of cilomilast and roflumilast.
Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 4 InhibitorsSynonyms: 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide, 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-p-anisamideAdenosine 3',5'-diphosphate
go.drugbank.com/drugs/DB01812ExperimentalCategories: Heterocyclic Compounds, 2-RingSynonyms: 3',5'-ADP, 3'-Phosphoadenosine 5'-phosphate