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Displaying results 3241 - 3250 of 10000 in total
  1. Drug

    Tecemotide

    go.drugbank.com/drugs/DB12568
    Investigational

    Tecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell Lung.

  2. Drug

    AZD-3043

    go.drugbank.com/drugs/DB12576
    Investigational

    AZD3043 has been used in trials studying the treatment and basic science of Safety, Sedation, Tolerability, and Pharmacokinetics.

  3. Drug

    JNJ-41443532

    go.drugbank.com/drugs/DB12632
    Investigational

    JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Samalizumab

    go.drugbank.com/drugs/DB12636
    Investigational

    Samalizumab has been used in trials studying the treatment of Multiple Myeloma and B-cell Chronic Lymphocytic Leukemia.

  5. Drug

    Nelivaptan

    go.drugbank.com/drugs/DB12643
    Investigational

    Nelivaptan has been used in trials studying the treatment of Anxiety Disorders, Depressive Disorder, and Major Depressive Disorder.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    VTP-194204

    go.drugbank.com/drugs/DB11806
    Investigational

    Nrx194204 has been used in trials studying the treatment of Parkinson's Disease and Non-small Cell Lung Cancer.

  7. Drug

    Prothipendyl

    go.drugbank.com/drugs/DB12958
    Investigational

    Prothipendyl has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  8. Target

    Integrin beta-7

    go.drugbank.com/bio_entities/BE0003414
    TargetHumans

    Integrin ITGAE/ITGB7 (alpha-E/beta-7, HML-1) is a receptor for E-cadherin (PubMed:10837471) … Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT) (Probable

    Synonyms: Gut homing receptor beta subunit
  9. Drug

    Arimoclomol

    go.drugbank.com/drugs/DB05025
    Approved

    Arimoclomol is a hydroxylamine derivative [A264414] and a heat-shock protein-70 (HSP70) co-inducer. … [L51384] Arimoclomol was approved by the FDA on September 20, 2024, making it the first treatment for Niemann-Pick disease, type C (NPC).

    Categories: MATE 1 Substrates, MATE 2 SubstratesSynonyms: 3-PYRIDINECARBOXIMIDOYL CHLORIDE, N-((2R)-2-HYDROXY-3-(1-PIPERIDINYL)PROPOXY), 1-OXIDE, N-[(2R)-2-Hydroxy-3-(1-piperidyl)propoxy]pyridine-3-carboximidoyl chloride, 1-oxide
  10. Drug

    Ziconotide

    go.drugbank.com/drugs/DB06283
    ApprovedInvestigational

    Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail _Conus magus_ comprising 25 amino acids with three disulphide bonds. … [A202829, A202832] Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling.

    Categories: N-Calcium Channel Receptor Antagonists, Calcium Channels, N-Type