Nelivaptan

DB12643InvestigationalSmall molecule

Nelivaptan has been used in trials studying the treatment of Anxiety Disorders, Depressive Disorder, and Major Depressive Disorder.

Mechanism: Pharmacologically active on Vasopressin V1b receptor
Curator reviewed
Formula / weight: C₃₀H₃₂ClN₃O₈S · 630.11 g/mol (avg)
Code names: SSR-149,415

Resolves to

Compound

UNII3TY57MQ4OACAS439687-69-1ChEMBLCHEMBL582857PubChem9895468

Structure

InChIKeyNJXZWIIMWNEOGJ-WEWKHQNJSA-NSMILES[H][C@]1(O)CN([C@@]([H])(C1)C(=O)N(C)C)[C@@]1(C(=O)N(C2=C1C=C(Cl)C=C2)S(=O)(=O)C1=C(OC)C=C(OC)C=C1)C1=CC=CC=C1OC

Targets

P47901AVPR1BP37288AVPR1AP30559OXTRP30518AVPR2

What you can answer from here — as of June 15, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Nelivaptan, and which of those have an active Phase 3 trial?

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