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Displaying results 3241 - 3250 of 4860 in total
  1. Drug

    Ethanolamine

    go.drugbank.com/drugs/DB03994
    Investigational

    It is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.

  2. Drug

    Cortisone

    go.drugbank.com/drugs/DB14681
    Investigational

    It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. … It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)

  3. Drug

    Thalagen

    go.drugbank.com/drugs/DB17714
    Experimental

    It is being investigated for the treatment of beta-thalassemia.[L46168] … It consists of autologous CD34-positive hematopoietic progenitor cells transduced with TNS9.3.55, a lentiviral vector encoding the normal human beta-globin gene.

  4. Drug

    Voclosporin

    go.drugbank.com/drugs/DB11693
    ApprovedInvestigational

    Lupus nephritis (LN) is a type of glomerulonephritis occurring in patients with systemic lupus erythematosus (SLE). LN is a significant cause of renal failure, morbidity, and death in patients with SLE. Within 10 years of being diagnosed...

  5. Drug

    Ganciclovir

    go.drugbank.com/drugs/DB01004
    ApprovedInvestigational

    An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.

    Products: Ganciclovir Oresund Pharma 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  6. Drug

    Erythropoietin

    go.drugbank.com/drugs/DB00016
    ApprovedInvestigational

    It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. … It has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced.

  7. Drug

    Viralym-C

    go.drugbank.com/drugs/DB17975
    Investigational

    It consists of Human Leukocyte Antigen (HLA)-matched cytomegalovirus (CMV)-specific T lymphocytes. … It was granted FDA orphan designation in January 2017 and investigated for the treatment of CMV infection.[A260291, L47241]

  8. Drug

    Zedenoleucel

    go.drugbank.com/drugs/DB18639
    Investigational

    MT-401 is an allogeneic multi-tumor-associated antigen-specific T-cell therapy.

  9. Drug

    Coenzyme A

    go.drugbank.com/drugs/DB01992
    InvestigationalNutraceutical

    It is used as a supplement for the hypothetical treatment of acne. … All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it, or a thioester form of it, as a substrate.

  10. Drug

    gamma-Butyrolactone

    go.drugbank.com/drugs/DB04699
    ExperimentalIllicit

    It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.