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Biopterin
go.drugbank.com/drugs/DB03886ExperimentalA natural product that has been considered as a growth factor for some insects. [PubChem]
Inebilizumab
go.drugbank.com/drugs/DB12530ApprovedInvestigationalInappropriate growth of or self-directed antibody production by B-cells is the etiological underpinning of a variety of conditions, including the multiple sclerosis-like neurological condition neuromyelitis optica spectrum disorder (NMOS...
Sparsentan
go.drugbank.com/drugs/DB12548ApprovedInvestigationalSparsentan is a dual antagonist of the endothelin type A receptor (ETAR) and the angiotensin II (Ang II) type 1 receptor (AT1R) with a similar affinity for both (9.3 nM for ETAR and 0.8 nM for AT1R). Sparsentan is first in its class and ...
L523S
go.drugbank.com/drugs/DB06498Investigational[A175909] It has been investigated as a lung cancer vaccine. … According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S)
Pexelizumab
go.drugbank.com/drugs/DB04949InvestigationalPexelizumab is a humanized monoclonal antibody used as an immunosuppressive drug. It is being investigated by Alexion Pharmaceuticals.
Sulopenem
go.drugbank.com/drugs/DB15284InvestigationalIt is marketed as the prodrug [sulopenem etzadroxil] in combination with [probenecid].[L51768]
OSU-6162
go.drugbank.com/drugs/DB19178InvestigationalOSU-6162 is under investigation in clinical trial NCT05641623 (OSU6162 as Add-on in Ssri/snri-resistant Depression).
TB-402
go.drugbank.com/drugs/DB06050InvestigationalIt is expected to be developed as a potential treatment to prevent blood clot formation in connection with certain types of heart arrhythmia, such as atrial fibrillation.
Z-Val-Ala-Asp fluoromethyl ketone
go.drugbank.com/drugs/DB07744ExperimentalNon-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes.
Butoconazole
go.drugbank.com/drugs/DB00639ApprovedButoconazole is an imidazole antifungal used in gynecology.