Search
Potassium cation
go.drugbank.com/drugs/DB01345ApprovedThe balance between potassium and sodium is maintained by ion pumps in the cell membrane. … The cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge.
Mixtures: POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 1000 CC SETLI, POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 1000 CC SETSİZSynonyms: Potassium ion, Potassium (ion)Helium
go.drugbank.com/drugs/DB09155ApprovedInvestigationalVet approvedIt is also used as an analytical reagent in diagnostic/imaging tests to detect respiratory function of the patient. … Helium is a second most abundant chemical element in the universe with symbol He and atomic number 2.
Mixtures: Oxygen In Helium Mix, Oxygen In Helium MixtureNonivamide
go.drugbank.com/drugs/DB11324ApprovedIt is naturally found in chili peppers but manufactured to produce a synthetic form for various pharmacologic preparations [L2641]. … Nonivamide is found in herbs and spices. It is an alkaloid from the Capsicum species.
Synonyms: N-Vanillylnonamide, N-Nonanoyl vanillylamideSilodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigational[A231159] Silodosin was first approved by the FDA in October 2008 [A231159] and it is also approved in Europe and Canada. … [A231159] Silodosin works by binding to α<sub>1A</sub>-adrenoceptors with high affinity and relaxing the lower urinary tract, thereby improving urinary symptoms and alleviating bladder outlet obstruction
Categories: Genito Urinary System and Sex Hormones, Drugs Used in Benign Prostatic HypertrophyLactitol
go.drugbank.com/drugs/DB12942Approved[A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.[L11803] … [A190912] Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides such as [lactulose], in the treatment of hepatic encephalopathy in
Categories: Compounds used in a research, industrial, or household setting, Diet, Food, and NutritionTisagenlecleucel
go.drugbank.com/drugs/DB13881ApprovedInvestigationalIt was granted approval by FDA in August 2017 under the market name Kymriah. … Tisagenlecleucel is an immunocellular therapy that involves autologous T cells that are collected from each individual patient and genetically engineered to express a specific protein called a chimeric
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic cell and gene therapyDuvelisib
go.drugbank.com/drugs/DB11952ApprovedInvestigationalcan produce a broad adaptative and innate immune cell inhibitory activity. … All the work around duvelisib showed that this agent is a potent inhibitor of both forms.[A39025] Duvelisib was developed by Verastem, Inc and FDA approved on September 24, 2018.[L4585]
Categories: Antineoplastic and Immunomodulating AgentsBesilesomab
go.drugbank.com/drugs/DB13979ApprovedUtilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like Italy, France, Germany, Spain, Portugal, Norway, Sweden, the … Netherlands, and the United Kingdom [L1564].
Categories: Amino Acids, Peptides, and ProteinsIL15-NK Cell
go.drugbank.com/drugs/DB15725InvestigationalIn particular, incubation with IL-15 allows NK cells to lyse a broad range of fresh and cultured tumor targets that the cell is not normally sensitive to. … Natural killer (NK) cells can be incubated with ‘feeder cells’ expressing certain cytokines prior to maturation to enhance their activity.
Synonyms: IL15-NK CellRelugolix
go.drugbank.com/drugs/DB11853ApprovedInvestigationalIt was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment of uterine fibroids,[A225816] and more recently by the United States' FDA in 2020, under the brand name … [A225926] In May 2021, the FDA approved the combination product made up of relugolix, [estradiol], and [norethindrone] under the market name Myfembree for the first once-daily treatment for the management
Categories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and Insulins