Lactitol is an orally administered osmotic laxative used to treat chronic idiopathic constipation. Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose.
- Mechanism
- Curator reviewed · 1 reference
Lactitol is an osmotic laxative - it exerts its pharmacologic effect by creating a hyperosmotic environment within the small intestine. The osmotic effect generated by lactitol draws water into the small intestine, which loosens stools and ultimately facilitates bowel movements.
- Primary indication
- Lactitol is indicated for the treatment of chronic idiopathic constipation in adults.Curator reviewed · 4 structured indications
- Formula / weight
- C12H24O11 · 344.3124 g/mol (avg)
- First approval
- United States, 2020
- Code names
- E-966 · INS-966 · INS NO.966 · NSC-231323
- Brand names
Resolves to
Clinical / RWD
Structure
InChIKey
VQHSOMBJVWLPSR-JVCRWLNRSA-NSMILESOC[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)COTargets
What you can answer from here — as of August 30, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Lactitol, and which of those have an active Phase 3 trial?
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