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Glycol salicylate
go.drugbank.com/drugs/DB11323ApprovedIt is found as an active ingredient and topical analgesic in patches used to provide relief for mild to moderate muscle and joint pain [L2686]. … This ingredient is an important component of many topical creams and sprays for the relief of aches, pains, and stiffness of the muscles, joints, and tendons [L2696].
Acellular nerve allograft
go.drugbank.com/drugs/DB30293ApprovedInvestigationalApproved by the FDA under a Biologics License Application (BLA) as an acellular nerve scaffold for the treatment of adult and pediatric patients (aged ≥1 month) with sensory, mixed, and motor peripheral
Isoflurophate
go.drugbank.com/drugs/DB00677ApprovedWithdrawnAn irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma.
Kinetin
go.drugbank.com/drugs/DB11336ApprovedWhile kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging agents.
Ethynodiol diacetate
go.drugbank.com/drugs/DB00823ApprovedA synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesReboxetine
go.drugbank.com/drugs/DB00234ApprovedInvestigationalWithdrawnReboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalPrecursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersAS1409
go.drugbank.com/drugs/DB05182InvestigationalThe other is an antibody that targets tumours. It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and melanoma.
Fosnetupitant
go.drugbank.com/drugs/DB14019ApprovedInvestigationaland Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg) as an … Considered one of the most distressing side effects of chemotherapy, nausea and vomiting has an immense impact on the quality of life of patients receiving certain antineoplastic therapies [A32865].
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates