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Ingenol mebutate
go.drugbank.com/drugs/DB05013ApprovedWithdrawnIngenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis. … PEP005 is a selective small molecule activator of protein kinase C (PKC) extracted from the plant Euphorbia peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions
Synonyms: Mebutato de ingenolReslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalthe first attack compared to patients receiving placebo [FDA Label, A31579]. … Asthma is a chronic respiratory disease that causes inflammation in the lungs with asthma attacks that lead to severe breathing difficulties.
Cladosporium cladosporioides
go.drugbank.com/drugs/DB10431ApprovedCladosporium cladosporioides is a fungus which can provoke allergic reactions. Cladosporium cladosporioides extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureTolazoline
go.drugbank.com/drugs/DB00797ApprovedVet approvedWithdrawnTolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. … It is used in treatment of persistent pulmonary hypertension of the newborn.
Categories: Adrenergic alpha-1 Receptor AntagonistsAV608
go.drugbank.com/drugs/DB05072InvestigationalIt is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).
Nicardipine
go.drugbank.com/drugs/DB00622ApprovedInvestigationalIt has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem] … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects.
Categories: Adrenergic alpha-1 Receptor AntagonistsCorticotropin
go.drugbank.com/drugs/DB01285ApprovedInvestigationalVet approvedCorticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis.
Flecainide
go.drugbank.com/drugs/DB01195ApprovedInvestigationalWithdrawn[A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.
Marstacimab
go.drugbank.com/drugs/DB17725ApprovedInvestigational[A264613] Marstacimab promotes hemostasis via the extrinsic pathway.[A264613] … [A264608] Marstacimab is used to prevent bleeding episodes in patients with hemophilia,[L51803] which is an X‐linked bleeding disorder characterized by coagulation clotting factor deficiency.