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RAV12
go.drugbank.com/drugs/DB05140InvestigationalRAV12 is a chimeric antibody that recognizes RAAG12, an N-linked carbohydrate antigen found on gastric, colon, pancreatic, prostate, ovarian, breast, and kidney cancer cells. … RAV12 is investigated for use/treatment in solid tumors. RAV12 is a solid.
Benmoxin
go.drugbank.com/drugs/DB09246ApprovedWithdrawnBenmoxin is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine class. It was first synthesized in 1967 and rapidly used in Europe as an antidepressant.
Guanidine
go.drugbank.com/drugs/DB00536Approved(From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC. … It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant.
Elacridar
go.drugbank.com/drugs/DB04881InvestigationalIn many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein inhibitors. As of August 2007 elacridar was not listed on GSK's product pipeline. … Elacridar (GW120918) is an oral bioenhancer that targets multiple drug resistance in tumors.
Piclidenoson
go.drugbank.com/drugs/DB05511InvestigationalCF101 is supplied as an oral drug and has an excellent safety profile. … CF 101 (known generically as IB-MECA) is an anti-inflammatory drug for rheumatoid arthritis patients. Its novel mechanism of action relies on antagonism of adenoside A3 receptors.
Vilazodone
go.drugbank.com/drugs/DB06684ApprovedInvestigationalVilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Culex pipiens
go.drugbank.com/drugs/DB14165ApprovedCulex pipiens allergenic extract is used in allergenic testing.
Sarocladium strictum
go.drugbank.com/drugs/DB14168ApprovedSarocladium strictum allergenic extract is used in allergenic testing.
Oportuzumab monatox
go.drugbank.com/drugs/DB05319InvestigationalVB4-845 is a fusion protein containing humanized scFv specific for the epithelial cell adhesion molecule, Ep-CAM, a tumor cell-associated target highly expressed on carcinoma cells of epithelial origin … VB4-845 is studied in the treatment of certain types of head and neck cancer. VB4-845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells.