Guanidine is a strong organic base used to treat muscle weakness and fatigue associated with the myasthenic complications of Eaton-Lambert syndrome. A strong organic base existing primarily as guanidium ions at physiological pH.
- Mechanism
- Curator reviewed
Pharmacologically active on Aldehyde dehydrogenase, mitochondrial and Voltage-gated Potassium Channels
- Primary indication
- For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert.Curator reviewed · 2 structured indications
- Formula / weight
- CH5N3 · 59.0705 g/mol (avg)
- First approval
- United States, 1939
- Also known as
- Aminomethanamidine · Guanidin · Imidourea · Iminourea
Resolves to
Clinical / RWD
Structure
InChIKey
ZRALSGWEFCBTJO-UHFFFAOYSA-NSMILESNC(N)=NWhat you can answer from here — as of September 23, 2026
8Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
8TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Guanidine, and which of those have an active Phase 3 trial?
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