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Lumefantrine
go.drugbank.com/drugs/DB06708ApprovedInvestigationalIt is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.
Abametapir
go.drugbank.com/drugs/DB11932ApprovedThe improved ovicidal activity (90-100% _in vitro_) of abemetapir allows for a single administration, in contrast to many other topical treatments, and its novel and relatively non-specific mechanism may … Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice.
Auranofin
go.drugbank.com/drugs/DB00995ApprovedInvestigationalAuranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and stimulate cell-mediated immunity. … It has subsequently been listed by the World Health Organization as a member of the antirheumatic agent category. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA.
RTA 744
go.drugbank.com/drugs/DB05920InvestigationalRTA 744 is a novel anthracycline derivative that crosses the blood-brain barrier and shows significant potential for the treatment of primary and metastatic brain cancers.
Clemastine
go.drugbank.com/drugs/DB00283ApprovedInvestigationalAn ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Categories: Antihistamines for Systemic Use, Antihistamines for Topical UseSAB-185
go.drugbank.com/drugs/DB16491InvestigationalCategories: Experimental Unapproved Treatments for COVID-19Rocaglamide
go.drugbank.com/drugs/DB15495Experimental[didesmethylrocaglamide]) are currently being studied for use as chemotherapeutic agents in the treatment of various leukemias, lymphomas, and carcinomas, as well as adjuvant therapy in the treatment of … Rocaglamide, also referred to as rocaglamide-A, is the eponymous member of a class of anti-cancer phytochemicals known as rocaglamides.
Amdinocillin
go.drugbank.com/drugs/DB01163ApprovedInvestigationalWithdrawnAmidinopenicillanic acid derivative with broad spectrum antibacterial action. It is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseIsoconazole
go.drugbank.com/drugs/DB08943ApprovedIsoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseProducts: ISOCONAZOL CREMA AL 1%, MICOBIP SOLUCION AL 1%Tolcapone
go.drugbank.com/drugs/DB00323ApprovedInvestigationalWithdrawnIt is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity. … Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.
Products: TASMAR ROCHE TABLETA LACADA DE 100 MG, TASMAR ROCHE TABLETAS LACADAS DE 200 MG